LIFR Products
(Leukemia Inhibitory Factor Receptor alpha (LIFR))
Categories
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5\;8)(p13\;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured LIFR Categories
LIFR Antibodies
High quality antibodies with extensive validation data.
LIFR ELISA Kits
Reliable ELISA kits for a wide range of species.
LIFR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LIFR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7437698
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7437992
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7432040
Quantity
100 μL
Datasheet
Datasheet
Recommended LIFR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6730977
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968279
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957463
Quantity
96 tests
Datasheet
Datasheet
Recommended LIFR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275152
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275153
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN2444162
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our LIFR products
: "Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 2, pp. 270-289, (2019) (PubMed).: "TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs." in: Journal of leukocyte biology, Vol. 102, Issue 2, pp. 423-436, (2017) (PubMed).
: "Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146281, (2016) (PubMed).
: "Leukemia Inhibitory Factor Is Necessary for Ovulation in Female Rhesus Macaques." in: Endocrinology, Vol. 157, Issue 11, pp. 4378-4387, (2016) (PubMed).
: "A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome." in: Genome biology, Vol. 17, Issue 1, pp. 108, (2016) (PubMed).
: "Expansive generation of functional airway epithelium from human embryonic stem cells." in: Stem cells translational medicine, Vol. 3, Issue 1, pp. 7-17, (2014) (PubMed).
: "Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer." in: Molecular and cellular biology, Vol. 30, Issue 17, pp. 4175-87, (2010) (PubMed).
: "Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells." in: Experimental cell research, Vol. 280, Issue 1, pp. 24-32, (2002) (PubMed).
Synonyms and alternative names related to LIFR
leukemia inhibitory factor receptor (Lifr), LIF receptor alpha (LOC397451), LIF receptor alpha (LIFR), LIF receptor alpha (Lifr), leukemia inhibitory factor receptor alpha (LIFR), A230075M04Rik, AW061234, CD118, LIF, LIF-R, SJS2, STWS, SWSProtein level used designations for LIFR
- D-factor/LIF receptor
- LIF receptor
- LIF-R
- leukemia inhibitory factor receptor alpha chain
- soluble differentiation-stimulating factor receptor
- CD118 antigen
- leukemia inhibitory factor receptor
- leukemia inhibitor factor receptor alpha-chain
- cytokine receptor-beta
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