Leptin Receptor Products
(Leptin Receptor (LEPR))
Categories
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010].
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Featured Leptin Receptor Categories
Leptin Receptor Antibodies
High quality antibodies with extensive validation data.
Leptin Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Leptin Receptor Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Leptin Receptor Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (7)
Cat. No.
ABIN7430873
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7430876
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7430879
Quantity
100 μL
Datasheet
Datasheet
Recommended Leptin Receptor ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963259
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957442
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963054
Quantity
96 tests
Datasheet
Datasheet
Recommended Leptin Receptor Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7319902
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7275141
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320922
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Leptin Receptor products
: "C-Peptide and leptin system in dichorionic, small and appropriate for gestational age twins-possible link to metabolic programming?" in: Nutrition & diabetes, Vol. 10, Issue 1, pp. 29, (2020) (PubMed).: "Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis." in: Frontiers in neuroscience, Vol. 14, pp. 219, (2020) (PubMed).
: "Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche." in: Cell reports, Vol. 26, Issue 12, pp. 3257-3271.e8, (2019) (PubMed).
: "Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B." in: JCI insight, Vol. 5, (2019) (PubMed).
: "Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow." in: Cell death & disease, Vol. 10, Issue 5, pp. 336, (2019) (PubMed).
: "N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells." in: Cell reports, Vol. 26, Issue 3, pp. 652-669.e6, (2019) (PubMed).
: "A spontaneous leptin receptor point mutation causes obesity and differentially affects leptin signaling in hypothalamic nuclei resulting in metabolic dysfunctions distinct from db/db mice." in: Molecular metabolism, Vol. 25, pp. 131-141, (2019) (PubMed).
: "Dietary protein restriction increases hepatic leptin receptor mRNA and plasma soluble leptin receptor in male rodents." in: PLoS ONE, Vol. 14, Issue 7, pp. e0219603, (2019) (PubMed).
: "Impaired natural killer cell subset phenotypes in human obesity." in: Immunologic research, Vol. 66, Issue 2, pp. 234-244, (2019) (PubMed).
: "Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration." in: The Journal of clinical investigation, Vol. 130, pp. 2578-2594, (2019) (PubMed).
Synonyms and alternative names related to Leptin Receptor
leptin receptor (LEPR), leptin receptor (lepr), leptin receptor (Lepr), leptin receptor S homeolog (lepr.S), CD295, cd295, db, diabetes, Fa, LEP-R, lepr, Leprb, LEPRD, LEPROT, Modb1, OB-R, Ob-R, ob-rb, OB-RGRP, Ob-RM, obese-like, obl, OBR, obr, Obr, ObRbProtein level used designations for Leptin Receptor
- OB receptor
- huB219
- LEP-R
- Leptin receptor (fatty)
- OB-R
- B219
- leptin receptor gene-related protein
- cytokine receptor
- leptin receptor long insert isoform
- leptin receptor
Did you look for something else?
- Leptin
- LEPROTL1
- LEPROT
- LEPREL2
- LEPREL1
- Leprecan-Like 4
- LEPRE1
- LEPB
- LEO1
- Lens Epithelial Protein
- LENG9
- LENG8
- Leng1
- LEMD3
- LEMD2
- LEMD1
- LELP1
- LEKR1
- Leishmanolysin-Like (Metallopeptidase M8 Family)
- Leishmania Lipophosphoglycan
- Leptospira Biflexa
- Leptospira IgM
- LETM1
- LETM2
- LETMD1
- Leucine Dehydrogenase
- Leucine Rich Repeat and Coiled-Coil Domain Containing 1
- Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing
- Leucine-Rich Repeat, Immunoglobulin-Like and Transmembrane Domains 1
- Leucine-Rich, Glioma Inactivated 1
- Leucoanthocyanidin Dioxygenase
- Leucokinin VIII
- LEUD2
- Leukocyte Antigen B27
- Leukoregulin
- Leukotriene A4
- Leukotriene B4
- Leukotriene B4 Receptor/BLT
- Leukotriene C4
- Leukotriene D4
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