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Leptin Products

(Leptin (LEP))

Categories

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].

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Featured Leptin Categories

Leptin Antibodies

High quality antibodies with extensive validation data.

Leptin ELISA Kits

Reliable ELISA kits for a wide range of species.

Leptin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Leptin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7445093
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7429181
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (4)
Cat. No. ABIN668243
Quantity 100 μL
Datasheet Datasheet

Recommended Leptin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (9)
  • (5)
Cat. No. ABIN6574137
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
  • (1)
Cat. No. ABIN365165
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6957438
Quantity 96 tests
Datasheet Datasheet

Recommended Leptin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275142
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320902
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
  • (1)
Cat. No. ABIN7538352
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Leptin products

Wen, Wang, Li, Shi, Liu: "Effect of xylo-oligosaccharides on reproduction, lipid metabolism, and adipokines of hens during the late egg-laying period." in: Animal bioscience, Vol. 35, Issue 11, pp. 1744-1751, (2022) (PubMed).

Faheem, Rehman, Jabeen, Akash: "Nicotine-mediated upregulation of microRNA-141 expression determines adipokine-intervened insulin resistance." in: Environmental toxicology and pharmacology, Vol. 80, pp. 103506, (2021) (PubMed).

Singh, Bansal, Sodhi, Khare, Bishnoi, Kondepudi, Medhi, Kuhad: "Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway." in: Toxicology and applied pharmacology, Vol. 402, pp. 115124, (2021) (PubMed).

Zierold, Buschmann, Gachkar, Bochenek, Velmeden, Hobohm, Vahl, Schäfer: "Brain-Derived Neurotrophic Factor Expression and Signaling in Different Perivascular Adipose Tissue Depots of Patients With Coronary Artery Disease." in: Journal of the American Heart Association, Vol. 10, Issue 6, pp. e018322, (2021) (PubMed).

Hue-Beauvais, Laubier, Brun, Houtia, Jaffrezic, Bevilacqua, Le Provost, Charlier: "Puberty is a critical window for the impact of diet on mammary gland development in the rabbit." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 248, Issue 10, pp. 948-960, (2020) (PubMed).

Wu, Guo, Li, Liu, Li, Lei, Yao, Yang: "Paternal chronic folate supplementation induced the transgenerational inheritance of acquired developmental and metabolic changes in chickens." in: Proceedings. Biological sciences, Vol. 286, Issue 1910, pp. 20191653, (2020) (PubMed).

Fan, Peng, Wu, Hu, Shi, Yang, Li: "Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis in pig model." in: Journal of ethnopharmacology, Vol. 249, pp. 112416, (2020) (PubMed).

Wang, Yin, Wang, Liu, Li, Li, Yi, Xiao: "Serum Asprosin Concentrations Are Increased and Associated with Insulin Resistance in Children with Obesity." in: Annals of nutrition & metabolism, Vol. 75, Issue 4, pp. 205-212, (2020) (PubMed).

Ezzat, El Bishbishy, Aborehab, Salama, Hasheesh, Motaal, Rashad, Metwally: "Upregulation of MC4R and PPAR-α expression mediates the anti-obesity activity of Moringa oleifera Lam. in high-fat diet-induced obesity in rats." in: Journal of ethnopharmacology, Vol. 251, pp. 112541, (2020) (PubMed).

Fan, Kuang, Dong, Yi, Zhou, Li, Qiao, Ye: "Prenylated Phenolic Compounds from the Aerial Parts of Glycyrrhiza uralensis as PTP1B and α-Glucosidase Inhibitors." in: Journal of natural products, Vol. 83, Issue 4, pp. 814-824, (2020) (PubMed).

Synonyms and alternative names related to Leptin

leptin (Lep), leptin (LEP), leptin (lep), LEPD, ob, OB, obese, OBS

Protein level used designations for Leptin

  • obesity factor
  • leptin (murine obesity homolog)
  • leptin (obesity homolog, mouse)
  • obese protein
  • obese, mouse, homolog of
  • obese
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