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LEO1 Products

(Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))

Categories

LEO1, parafibromin (CDC73\; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008].

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Featured LEO1 Categories

LEO1 Antibodies

High quality antibodies with extensive validation data.

LEO1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LEO1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6133790
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7140122
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN1387569
Quantity 100 μL
Datasheet Datasheet

Recommended LEO1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6205534
Quantity 96 tests
Datasheet Datasheet

Recommended LEO1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309305
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724642
Quantity 20 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Source Yeast
Validations
Cat. No. ABIN1478082
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our LEO1 products

Willmann, Milosevic, Pauklin, Schmitz, Rangam, Simon, Maslen, Skehel, Robert, Heyer, Schiavo, Reina-San-Martin, Petersen-Mahrt: "A role for the RNA pol II-associated PAF complex in AID-induced immune diversification." in: The Journal of experimental medicine, Vol. 209, Issue 11, pp. 2099-111, (2012) (PubMed).

Miyazaki, Inoue, Yamada, Watanabe, Liu, Watanabe, Adachi, Tanaka, Kitajima: "Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells." in: Nucleic acids research, Vol. 37, Issue 5, pp. 1438-51, (2009) (PubMed).

Zhu, Mandal, Pham, Zheng, Erdjument-Bromage, Batra, Tempst, Reinberg: "The human PAF complex coordinates transcription with events downstream of RNA synthesis." in: Genes & development, Vol. 19, Issue 14, pp. 1668-73, (2005) (PubMed).

Zhao, Tong, Zhang: "Expression of the Leo1-like domain of replicative senescence down-regulated Leo1-like (RDL) protein promotes senescence of 2BS fibroblasts." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 6, pp. 521-32, (2005) (PubMed).

Rozenblatt-Rosen, Hughes, Nannepaga, Shanmugam, Copeland, Guszczynski, Resau, Meyerson: "The parafibromin tumor suppressor protein is part of a human Paf1 complex." in: Molecular and cellular biology, Vol. 25, Issue 2, pp. 612-20, (2005) (PubMed).

Rondón, Gallardo, García-Rubio, Aguilera: "Molecular evidence indicating that the yeast PAF complex is required for transcription elongation." in: EMBO reports, Vol. 5, Issue 1, pp. 47-53, (2004) (PubMed).

Synonyms and alternative names related to LEO1

LEO1 homolog, Paf1/RNA polymerase II complex component (LEO1), Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (leo1), RNA polymerase-associated protein LEO1 (LOC100466503), LEO1 homolog, Paf1/RNA polymerase II complex component (leo1), LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog (leo1.S), Leo1, Paf1/RNA polymerase II complex component (Leo1), Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (LOC415420), RNA polymerase-associated protein LEO1 (LOC478310), LEO1 homolog, Paf1/RNA polymerase II complex component (Leo1), Gm185, LEO1, RDL, zgc:77374

Protein level used designations for LEO1

  • Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • RNA polymerase-associated protein LEO1
  • RNA polymerase-associated protein LEO1-like
  • replicative senescence down-regulated leo1-like protein
  • Paf1/RNA polymerase II complex component
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