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LCLAT1 Products

(Lysocardiolipin Acyltransferase 1 (LCLAT1))

Categories

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

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Featured LCLAT1 Categories

LCLAT1 Antibodies

High quality antibodies with extensive validation data.

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Latest Publications for our LCLAT1 products

Eirin, Ebrahimi, Kwon, Fiala, Williams, Woollard, He, Gupta, Sabbah, Prakash, Textor, Lerman, Lerman: "Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension." in: Journal of the American Heart Association, Vol. 5, Issue 6, (2016) (PubMed).

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).

Synonyms and alternative names related to LCLAT1

lysocardiolipin acyltransferase 1 (lclat1), lysocardiolipin acyltransferase 1 (LCLAT1), lysocardiolipin acyltransferase 1 (Lclat1), 1agpat8, 1AGPAT8, agpat8, AGPAT8, Agpat8, AGPATP8, AI181996, alcat1, ALCAT1, Alcat1, Gm91, HSRG1849, lclat1, LYCAT, lycat, Lycat, RGD1565906, UNQ1849, wu:fj17g04, zgc:77380

Protein level used designations for LCLAT1

  • lysocardiolipin acyltransferase 1
  • 1-acylglycerol-3-phosphate O-acyltransferase 8
  • 1-AGP acyltransferase 8
  • 1-AGPAT 8
  • acyl-CoA:lysocardiolipin acyltransferase 1
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