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LAT2 Products

(Linker For Activation of T Cells Family, Member 2 (LAT2))
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008].

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Featured LAT2 Categories

LAT2 Antibodies

High quality antibodies with extensive validation data.

LAT2 ELISA Kits

Reliable ELISA kits for a wide range of species.

LAT2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LAT2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IP, ICC, FACS
Validations
  • (5)
  • (6)
Cat. No. ABIN94439
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439774
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (12)
Cat. No. ABIN7074503
Quantity 100 μL
Datasheet Datasheet

Recommended LAT2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884009
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384759
Quantity 96 tests
Datasheet Datasheet

Recommended LAT2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123772
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309187
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309189
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our LAT2 products

Duque-Afonso, Yalcin, Berg, Abdelkarim, Heidenreich, Lübbert: "The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO." in: Oncogene, Vol. 30, Issue 27, pp. 3062-72, (2011) (PubMed).

Lebduska, Korb, T?mová, Heneberg, Dráber: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." in: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).

Nørsett, Laegreid, Langaas, Wörlund, Fossmark, Waldum, Sandvik: "Molecular characterization of rat gastric mucosal response to potent acid inhibition." in: Physiological genomics, Vol. 22, Issue 1, pp. 24-32, (2007) (PubMed).

Heneberg, Lebduska, Dráberová, Korb, Dráber: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." in: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).

Tkaczyk, Horejsi, Iwaki, Draber, Samelson, Satterthwaite, Nahm, Metcalfe, Gilfillan: "NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation." in: Blood, Vol. 104, Issue 1, pp. 207-14, (2004) (PubMed).

Volná, Lebduska, Dráberová, Símová, Heneberg, Boubelík, Bugajev, Malissen, Wilson, Horejsí, Malissen, Dráber: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).

Brdicka, Imrich, Angelisová, Brdicková, Horváth, Spicka, Hilgert, Lusková, Dráber, Novák, Engels, Wienands, Simeoni, Osterreicher, Aguado, Malissen, Schraven, Horejsí: "Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling." in: The Journal of experimental medicine, Vol. 196, Issue 12, pp. 1617-26, (2002) (PubMed).

Synonyms and alternative names related to LAT2

linker for activation of T-cells family member 2 (LAT2), linker for activation of T cells family, member 2 (LAT2), linker for activation of T cells family, member 2 (Lat2), AW125574, LAB, LAT2, MGC139435, NTAL, Ntal, WBSCR5, Wbscr5, WBSCR15, Wbscr15, WSCR5

Protein level used designations for LAT2

  • Williams-Beuren syndrome chromosomal region 15 protein
  • Williams-Beuren syndrome chromosomal region 5 protein
  • linker for activation of B-cells
  • linker for activation of T cells, transmembrane adaptor 2
  • linker for activation of T-cells family member 2
  • membrane-associated adapter molecule
  • non-T-cell activation linker
  • Williams-Beuren syndrome chromosome region 5 homolog
  • non-T cell activation linker
  • linker for activation of T cells family, member 2
  • Williams-Beuren syndrome chromosome region 5-like protein
  • Williams-Beuren syndrome chromosome region 15 homolog
  • williams-Beuren syndrome chromosomal region 15 protein homolog
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