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LASP1 Products

(LIM and SH3 Protein 1 (LASP1))
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012].

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Featured LASP1 Categories

LASP1 Antibodies

High quality antibodies with extensive validation data.

LASP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LASP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LASP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (6)
Cat. No. ABIN1680664
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF
Validations
  • (4)
Cat. No. ABIN7158350
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN3044177
Quantity 100 μg
Datasheet Datasheet

Recommended LASP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957479
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975072
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1140655
Quantity 96 tests
Datasheet Datasheet

Recommended LASP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309166
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2130290
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409455
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LASP1 products

Yu, Baird, Allen, Howe, Klassen, Reade, Makhijani, Song, Liu, Murthy, Zhang, Weiner, Kornberg, Jan, Davidson, Shu: "A naturally monomeric infrared fluorescent protein for protein labeling in vivo." in: Nature methods, Vol. 12, Issue 8, pp. 763-5, (2015) (PubMed).

Ngan, Northey, Brown, Ursini-Siegel, Siegel: "A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells." in: Journal of cell science, Vol. 126, Issue Pt 9, pp. 1981-91, (2013) (PubMed).

Stone, Merriman, Cantor, Geschwind, Nelson: "High density SNP association study of a major autism linkage region on chromosome 17." in: Human molecular genetics, Vol. 16, Issue 6, pp. 704-15, (2007) (PubMed).

Grunewald, Kammerer, Schulze, Schindler, Honig, Zimmer, Butt: "Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells." in: Experimental cell research, Vol. 312, Issue 7, pp. 974-82, (2006) (PubMed).

Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).

Li, Hornshaw, van Minnen, Smalla, Gundelfinger, Smit et al.: "Organelle proteomics of rat synaptic proteins: correlation-profiling by isotope-coded affinity tagging in conjunction with liquid chromatography-tandem mass spectrometry to reveal post-synaptic ..." in: Journal of proteome research, Vol. 4, Issue 3, pp. 725-33, (2005) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, (2003) (PubMed).

Schreiber, Moog-Lutz, Régnier, Chenard, Boeuf, Vonesch, Tomasetto, Rio: "Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions." in: Molecular medicine (Cambridge, Mass.), Vol. 4, Issue 10, pp. 675-87, (1999) (PubMed).

Tomasetto, Régnier, Moog-Lutz, Mattei, Chenard, Lidereau, Basset, Rio: "Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17." in: Genomics, Vol. 28, Issue 3, pp. 367-76, (1996) (PubMed).

Synonyms and alternative names related to LASP1

LIM and SH3 protein 1 (lasp1), LIM and SH3 protein 1 L homeolog (lasp1.L), LIM and SH3 protein 1 (LASP1), LIM and SH3 protein 1 (Lasp1), AA408629, Def-4, fb92f05, Lasp-1, lasp-1, lasp1, LASP1, MGC53336, MGC89667, MLN50, mln50, SH3P6, Tg(Col1a1-lacZ)1Ngma, wu:fb92f05, zgc:77542

Protein level used designations for LASP1

  • LIM and SH3 domain protein 1
  • LIM and SH3 protein 1
  • lasp1 protein
  • metastatic lymph node gene 50 protein
  • LASP-1
  • MLN 50
  • Tg(11Col1a1)NG
  • 40 kDa phosphoprotein
  • phosphoprotein Lasp-1
  • pp40
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