LARP6 Products
(La Ribonucleoprotein Domain Family, Member 6 (LARP6))
Categories
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9 (By similarity).
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Featured LARP6 Categories
LARP6 Antibodies
High quality antibodies with extensive validation data.
LARP6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LARP6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN654784
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (8)
- (2)
Cat. No.
ABIN527496
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7157812
Quantity
100 μg
Datasheet
Datasheet
Recommended LARP6 Proteins
Latest Publications for our LARP6 products
: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).
: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).
: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).
: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).
: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).
: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).
: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).
Synonyms and alternative names related to LARP6
La ribonucleoprotein domain family, member 6b (larp6b), La ribonucleoprotein domain family member 6 (LARP6), La ribonucleoprotein domain family, member 6 (Larp6), 5430431G03Rik, ACHN, Achn, AI552438, im:7142825, RGD1308414, wu:fa55b04Protein level used designations for LARP6
- La ribonucleoprotein domain family, member 6
- acheron
- death-associated LA motif protein
- la-related protein 6
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