LAP Products
(Leucine Aminopeptidase (LAP))
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This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10\;11)(p13\;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
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Featured LAP Categories
LAP Antibodies
High quality antibodies with extensive validation data.
LAP ELISA Kits
Reliable ELISA kits for a wide range of species.
LAP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LAP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1859614
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1862838
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Pig
Application
WB, ELISA, IF
Validations
Cat. No.
ABIN458923
Quantity
1 mg
Datasheet
Datasheet
Recommended LAP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957444
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957445
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1570980
Quantity
96 tests
Datasheet
Datasheet
Recommended LAP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390799
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390802
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3010450
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LAP products
: "In Vivo Two-Photon Fluorescence Imaging of the Activity of the Inflammatory Biomarker LTA4H in a Mouse Pneumonia Model." in: Analytical chemistry, Vol. 90, Issue 10, pp. 6020-6027, (2019) (PubMed).: "Detection of low-concentration host mRNA transcripts in Malawian children at risk for environmental enteropathy." in: Journal of pediatric gastroenterology and nutrition, Vol. 56, Issue 1, pp. 66-71, (2013) (PubMed).
Synonyms and alternative names related to LAP
leucine aminopeptidase (PVX_118180), leucine aminopeptidase (CpipJ_CPIJ002841), leucine aminopeptidase (lap), leucine aminopeptidase (pepA), leucine aminopeptidase (NAEGRDRAFT_78195), leucine aminopeptidase (TP04_0561), leucine aminopeptidase (BBOV_II004450), leucine aminopeptidase, putative (PKH_126020), leucine aminopeptidase (NAEGRDRAFT_82309), phosphatidylinositol binding clathrin assembly protein (PICALM), phosphatidylinositol binding clathrin assembly protein (Picalm), 18.m06372, CALM, Calm, CLTH, DDBDRAFT_0218188, DDBDRAFT_0231024, DDB_0218188, DDB_0231024, LAPProtein level used designations for LAP
- leucine aminopeptidase
- clathrin assembly lymphoid myeloid leukemia protein
- phosphatidylinositol-binding clathrin assembly protein
- clathrin-assembly lymphoid leukemia protein
- clathrin-assembly lymphoid myeloid leukemia protein
- rCALM
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