LAMTOR1 Products
(Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))
Categories
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation (By similarity).
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Featured LAMTOR1 Categories
LAMTOR1 Antibodies
High quality antibodies with extensive validation data.
LAMTOR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LAMTOR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LAMTOR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (3)
Cat. No.
ABIN6143083
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7167068
Quantity
100 μg
Datasheet
Datasheet
Recommended LAMTOR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968205
Quantity
96 tests
Datasheet
Datasheet
Recommended LAMTOR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Xenopus tropicalis
Source
Yeast
Validations
Cat. No.
ABIN1675037
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LAMTOR1 products
: "LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy." in: Cellular microbiology, Vol. 21, Issue 4, pp. e12981, (2019) (PubMed).: "mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival." in: The EMBO journal, Vol. 34, Issue 17, pp. 2272-90, (2015) (PubMed).
: "The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection." in: Journal of cell science, Vol. 125, Issue Pt 11, pp. 2698-708, (2012) (PubMed).
: "MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB." in: Autophagy, Vol. 8, Issue 6, pp. 903-14, (2012) (PubMed).
: "Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts." in: Proteomics, Vol. 10, Issue 22, pp. 4117-27, (2010) (PubMed).
Synonyms and alternative names related to LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (LAMTOR1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (Lamtor1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog (lamtor1.S), 2400001E08Rik, C11orf59, c11orf59, C15H11orf59, flj20625, p18, p27RF-Rho, p27rf-rho, PDRO, Pdro, pdro, Ragulator1, ragulator1Protein level used designations for LAMTOR1
- RhoA activator C11orf59
- late endosomal/lysosomal adaptor and MAPK and MTOR activator 1
- lipid raft adaptor protein p18
- p27Kip1-releasing factor from RhoA
- p27kip1 releasing factor from RhoA
- protein associated with DRMs and endosomes
- ragulator complex protein LAMTOR1
- ragulator complex protein PDRO
- RhoA activator C11orf59 homolog
- p27RF-Rho
- rhoA activator C11orf59 homolog
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