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Lamin B2 Products

(Lamin B2 (LMNB2))
This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012].

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Featured Lamin B2 Categories

Lamin B2 Antibodies

High quality antibodies with extensive validation data.

Lamin B2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Lamin B2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Lamin B2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (10)
Cat. No. ABIN5542337
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (7)
Cat. No. ABIN7262334
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (14)
Cat. No. ABIN6143268
Quantity 100 μL
Datasheet Datasheet

Recommended Lamin B2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957378
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1139989
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1139987
Quantity 96 tests
Datasheet Datasheet

Recommended Lamin B2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408168
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724479
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6380927
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Lamin B2 products

Morinishi, Tokuhara, Ohsaki, Ibuki, Kadota, Hirakawa: "Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma." in: PPAR research, Vol. 2019, pp. 7486727, (2019) (PubMed).

Chen, Jiang, Gu, Lai, Liu, Zhang: "Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway." in: Environmental toxicology, Vol. 32, Issue 8, pp. 2004-2020, (2017) (PubMed).

Jevti?, Edens, Li, Nguyen, Chen, Levy: "Concentration-dependent Effects of Nuclear Lamins on Nuclear Size in Xenopus and Mammalian Cells." in: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27557-71, (2015) (PubMed).

Jacinto, Benner, Hetzer: "The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing." in: Genes & development, Vol. 29, Issue 12, pp. 1224-38, (2015) (PubMed).

Tsai, Lee, Lin: "Ribosome distribution in HeLa cells during the cell cycle." in: PLoS ONE, Vol. 7, Issue 3, pp. e32820, (2012) (PubMed).

Shimi, Butin-Israeli, Adam, Hamanaka, Goldman, Lucas, Shumaker, Kosak, Chandel, Goldman: "The role of nuclear lamin B1 in cell proliferation and senescence." in: Genes & development, Vol. 25, Issue 24, pp. 2579-93, (2011) (PubMed).

Taimen, Pfleghaar, Shimi, Möller, Ben-Harush, Erdos, Adam, Herrmann, Medalia, Collins, Goldman, Goldman: "A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20788-93, (2010) (PubMed).

Ishimoto, Nakamura, Tachibana, Yamasaki, Ota, Hirano, Tanaka, Hamakubo, Sakai, Kodama, Doi: "Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22195-205, (2009) (PubMed).

Mackay, Elgort, Ullman: "The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis." in: Molecular biology of the cell, Vol. 20, Issue 6, pp. 1652-60, (2009) (PubMed).

Hisatsune, Nakayama, Isomoto, Kurazono, Mukaida, Mukhopadhyay, Azuma, Yamaoka, Sap, Yamasaki, Yahiro, Moss, Hirayama et al.: "Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 5017-27, (2008) (PubMed).

Synonyms and alternative names related to Lamin B2

lamin B2 S homeolog (lmnb2.S), lamin B2 (LMNB2), lamin B2 (lmnb2), lamin B2 L homeolog (lmnb2.L), lamin B2 (Lmnb2), im:7142331, lamb2, LAMB2, lamin, lamin-b2, Lamin-L(II), lmn2, LMN2, LMNB2, lmnb2, lmnb2-a, LOC100136040, RGD1563803, wu:fb94e05, wu:fb95e12, wu:fc15d06, wu:fc49h03

Protein level used designations for Lamin B2

  • lamin B2
  • lamin-B2-like
  • fc15d06
  • lamin-B2
  • lamin LII
  • lamin-L(II)
  • lamin B3
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