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LAIR1 Products

(Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

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The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008].

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Featured LAIR1 Categories

LAIR1 Antibodies

High quality antibodies with extensive validation data.

LAIR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LAIR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LAIR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IP
Validations
  • (6)
  • (3)
Cat. No. ABIN1690731
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN5684133
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7158291
Quantity 100 μg
Datasheet Datasheet

Recommended LAIR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968286
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957470
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883563
Quantity 96 tests
Datasheet Datasheet

Recommended LAIR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275118
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275117
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275119
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LAIR1 products

Achieng, Guyah, Cheng, Ongecha, Ouma, Lambert, Perkins: "Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling." in: EBioMedicine, (2019) (PubMed).

Ramos-Amaya, Rodríguez-Bayona, López-Blanco, Andújar, Pérez-Alegre, Campos-Caro, Brieva: "Survival of human circulating antigen-induced plasma cells is supported by plasma cell-niche cytokines and T follicular helper lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 3, pp. 1031-8, (2015) (PubMed).

Colombo, Canevali, Magnani, Rossi, Puppo, Zocchi, Poggi: "Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients." in: PLoS ONE, Vol. 7, Issue 2, pp. e31903, (2012) (PubMed).

Son, Santiago-Schwarz, Al-Abed, Diamond: "C1q limits dendritic cell differentiation and activation by engaging LAIR-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 46, pp. E3160-7, (2012) (PubMed).

White, Rämer, Naresh, Meixlsperger, Pinaud, Rooney, Savoldo, Coutinho, Bödör, Gribben, Ibrahim, Bower, Nourse, Gandhi, Middeldorp, Cader, Murray, Münz, Allday: "EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors." in: The Journal of clinical investigation, Vol. 122, Issue 4, pp. 1487-502, (2012) (PubMed).

Rodríguez-Bayona, Ramos-Amaya, Brieva: "Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation." in: Immunology letters, Vol. 134, Issue 2, pp. 122-8, (2010) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Tang, Narayanan, Peruzzi, Apara, Natarajan, Margulies, Coligan, Borrego: "A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 9, pp. 5446-52, (2009) (PubMed).

Meyaard: "The inhibitory collagen receptor LAIR-1 (CD305)." in: Journal of leukocyte biology, Vol. 83, Issue 4, pp. 799-803, (2008) (PubMed).

Synonyms and alternative names related to LAIR1

leukocyte-associated Ig-like receptor 1 (Lair1), leukocyte associated immunoglobulin like receptor 1 (LAIR1), leukocyte-associated immunoglobulin-like receptor 1 (Lair1), 5133400O11Rik, BB115266, CD305, D7Bwg0421e, Lair-1, LAIR-1, mLair-1

Protein level used designations for LAIR1

  • leukocyte-associated immunoglobulin-like receptor 1
  • mLAIR1
  • hLAIR1
  • leukocyte-associated Ig-like receptor 1
  • LAIR-1
  • leukocyte-associated Ig-like receptor-1
  • rLAIR1
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