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LAG3 Products

(Lymphocyte-Activation Gene 3 (LAG3))

Categories

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008].

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Featured LAG3 Categories

LAG3 Antibodies

High quality antibodies with extensive validation data.

LAG3 ELISA Kits

Reliable ELISA kits for a wide range of species.

LAG3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LAG3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (7)
Cat. No. ABIN652269
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN5684122
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN3028809
Quantity 0.4 mL
Datasheet Datasheet

Recommended LAG3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968380
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957563
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957564
Quantity 96 tests
Datasheet Datasheet

Recommended LAG3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (7)
Cat. No. ABIN7275113
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275114
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275115
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LAG3 products

Scheper, Kelderman, Fanchi, Linnemann, Bendle, de Rooij, Hirt, Mezzadra, Slagter, Dijkstra, Kluin, Snaebjornsson, Milne, Nelson, Zijlmans, Kenter, Voest, Haanen, Schumacher: "Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers." in: Nature medicine, Vol. 25, Issue 1, pp. 89-94, (2019) (PubMed).

Franchini, Lanvin, Tosolini, Patras de Campaigno, Cammas, Péricart, Scarlata, Lebras, Rossi, Ligat, Pont, Arimondo, Laurent, Ayyoub, Despas, Lapeyre-Mestre, Millevoi, Fournié: "Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells." in: Cell reports, Vol. 26, Issue 1, pp. 94-107.e7, (2019) (PubMed).

Yu, Huang, Chen, Liu, Wu, Pu, Wang, Kang, Zhou: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).

Umeshappa, Singha, Blanco, Shao, Nanjundappa, Yamanouchi, Parés, Serra, Yang, Santamaria: "Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines." in: Nature communications, Vol. 10, Issue 1, pp. 2150, (2019) (PubMed).

Choi, Maeng, Lee, Kim, Kim, Lee, Namgung, Oh, Kim, Jeong, Park, Choi, Kang, Yoon, Lee: "Diagnostic value of peripheral blood immune profiling in colorectal cancer." in: Annals of surgical treatment and research, Vol. 94, Issue 6, pp. 312-321, (2018) (PubMed).

DAngelo, Melchiori, Merchant, Bernstein, Glod, Kaplan, Grupp, Tap, Chagin, Binder, Basu, Lowther, Wang, Bath, Tipping, Betts, Ramachandran, Navenot, Zhang, Wells, Van Winkle, Kari, Trivedi, Holdich et al.: "Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma. ..." in: Cancer discovery, Vol. 8, Issue 8, pp. 944-957, (2018) (PubMed).

Sukumaran, Watanabe, Bajgain, Raja, Mohammed, Fisher, Brenner, Leen, Vera: "Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment." in: Cancer discovery, Vol. 8, Issue 8, pp. 972-987, (2018) (PubMed).

Péricart, Tosolini, Gravelle, Rossi, Traverse-Glehen, Amara, Franchet, Martin, Bezombes, Laurent, Brousset, Fournié, Laurent: "Profiling Immune Escape in Hodgkin's and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining." in: Cancers, Vol. 10, Issue 11, (2018) (PubMed).

Wang, Ti, Wang, Guo, Jiang, Chang, Qian, Zhao, Sun: "LAG-3 Represents a Marker of CD4+ T Cells with Regulatory Activity in Patients with Bone Fracture." in: Immunological investigations, Vol. 47, Issue 5, pp. 492-503, (2018) (PubMed).

Chen, Huang, Lu, Wang, Chi: "Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation." in: Oncology reports, Vol. 40, Issue 6, pp. 3370-3380, (2018) (PubMed).

Synonyms and alternative names related to LAG3

lymphocyte activating 3 (LAG3), lymphocyte-activation gene 3 (Lag3), lymphocyte activating 3 (Lag3), CD223, LAG-3, Ly66

Protein level used designations for LAG3

  • lymphocyte-activation gene 3
  • lymphocyte-activation protein 3
  • lymphocyte-activation protein 3-like
  • lymphocyte activation gene 3 protein-like
  • lymphocyte activation gene 3 protein
  • LAG-3
  • lymphocyte activation gene 3
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