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Kv2.2 Products

(Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells. [provided by RefSeq, Jul 2008].

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Featured Kv2.2 Categories

Kv2.2 Antibodies

High quality antibodies with extensive validation data.

Kv2.2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Kv2.2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kv2.2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881474
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1386740
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC
Validations
  • (1)
Cat. No. ABIN305657
Quantity 100 μL
Datasheet Datasheet

Recommended Kv2.2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6969456
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210723
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210722
Quantity 96 tests
Datasheet Datasheet

Recommended Kv2.2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3117144
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130917
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Kv2.2 products

Wang, Huang, Zhou, Mei: "GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells." in: The Biochemical journal, Vol. 460, Issue 1, pp. 35-47, (2014) (PubMed).

Dufour, Woodhouse, Goaillard: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).

Tsantoulas, Zhu, Shaifta, Grist, Ward, Raouf, Michael, McMahon: "Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 48, pp. 17502-13, (2012) (PubMed).

Zhuang, Wang, Zhou, Duan, Mei: "TGF-?1 enhances Kv2.1 potassium channel protein expression and promotes maturation of cerebellar granule neurons." in: Journal of cellular physiology, Vol. 227, Issue 1, pp. 297-307, (2011) (PubMed).

Kyle, Bradley, Ohya, Sergeant, McHale, Thornbury, Hollywood: "Contribution of Kv2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra." in: American journal of physiology. Cell physiology, Vol. 301, Issue 5, pp. C1186-200, (2011) (PubMed).

Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: "Common genetic variation and performance on standardized cognitive tests." in: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, (2010) (PubMed).

Kihira, Hermanstyne, Misonou: "Formation of heteromeric Kv2 channels in mammalian brain neurons." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 15048-55, (2010) (PubMed).

Hermanstyne, Kihira, Misono, Deitchler, Yanagawa, Misonou: "Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice." in: The Journal of comparative neurology, Vol. 518, Issue 21, pp. 4298-310, (2010) (PubMed).

Baranzini, Wang, Gibson, Galwey, Naegelin, Barkhof, Radue, Lindberg, Uitdehaag, Johnson, Angelakopoulou, Hall, Richardson, Prinjha, Gass, Geurts, Kragt, Sombekke, Vrenken, Qualley, Lincoln et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." in: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, (2009) (PubMed).

Gravagna, Knoeckel, Taylor, Hultgren, Ribera: "Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 508-24, (2008) (PubMed).

Synonyms and alternative names related to Kv2.2

potassium voltage-gated channel subfamily B member 2 (KCNB2), potassium voltage-gated channel, Shab-related subfamily, member 2 (kcnb2), potassium voltage-gated channel subfamily B member 2 (LOC100051372), potassium channel, voltage gated Shab related subfamily B, member 2 (kcnb2), potassium voltage-gated channel subfamily B member 2 (Kcnb2), potassium voltage gated channel, Shab-related subfamily, member 2 (Kcnb2), potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog (kcnb2.S), potassium voltage-gated channel, Shab-related subfamily, member 2 (KCNB2), 9630047L19Rik, BB130875, KCNB2, kcnb2, Kv2.2, KV2.2, si:ch211-193n21.1, XShab12

Protein level used designations for Kv2.2

  • potassium voltage-gated channel, Shab-related subfamily, member 2
  • potassium voltage-gated channel subfamily B member 2-like
  • CDRK
  • potassium voltage-gated channel subfamily B member 2
  • voltage-gated potassium channel subunit Kv2.2
  • potassium voltage-gated channel, Shab-related subfamily, member 2, potassium channel alpha subunit Kv2.2
  • delayed rectifier potassium channel protein
  • potassium channel Kv2.2
  • voltage-gated potassium channel alpha subunit Kv2.2
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