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Kv2.1/KCNB1 Products

(Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008].

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Featured Kv2.1/KCNB1 Categories

Kv2.1/KCNB1 Antibodies

High quality antibodies with extensive validation data.

Kv2.1/KCNB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kv2.1/KCNB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
  • (9)
Cat. No. ABIN3043866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7163961
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6740360
Quantity 100 μL
Datasheet Datasheet

Recommended Kv2.1/KCNB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210721
Quantity 96 tests
Datasheet Datasheet

Recommended Kv2.1/KCNB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124533
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3114880
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134822
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Kv2.1/KCNB1 products

Ednie, Bennett: "Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly." in: The Journal of biological chemistry, Vol. 290, Issue 5, pp. 2769-83, (2015) (PubMed).

Liu, Magri, Zhang, Marsh, Albrecht, Huynh, Kaur, Kuhlmann, Zhang, Slesinger, Casaccia: "Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 1, pp. 352-65, (2015) (PubMed).

Nieves-Cintrón, Nystoriak, Prada, Johnson, Fayer, DellAcqua, Scott, Navedo: "Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7918-29, (2015) (PubMed).

Moutal, François-Moutal, Brittain, Khanna, Khanna: "Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides." in: Frontiers in cellular neuroscience, Vol. 8, pp. 471, (2015) (PubMed).

Fox, Haberkorn, Akin, Seel, Krapf, Tamkun: "Induction of stable ER-plasma-membrane junctions by Kv2.1 potassium channels." in: Journal of cell science, Vol. 128, Issue 11, pp. 2096-105, (2015) (PubMed).

Vullhorst, Mitchell, Keating, Roychowdhury, Karavanova, Tao-Cheng, Buonanno: "A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling." in: Nature communications, Vol. 6, pp. 7222, (2015) (PubMed).

He, McCord, Hartnett, Aizenman: "Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K+ Channels." in: PLoS ONE, Vol. 10, Issue 6, pp. e0129498, (2015) (PubMed).

Jensen, Misonou: "Live-cell imaging of post-golgi transport vesicles in cultured hippocampal neurons." in: Cellular and molecular neurobiology, Vol. 35, Issue 1, pp. 123-35, (2015) (PubMed).

El Gebeily, El Khoury, Mathieu, Brouillette, Fiset: "Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 86, pp. 85-94, (2015) (PubMed).

Krasowska, Zabłocki, Górecki, Swinny: "Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice: implications for cognitive impairment in duchenne muscular dystrophy." in: PLoS ONE, Vol. 9, Issue 9, pp. e108364, (2014) (PubMed).

Synonyms and alternative names related to Kv2.1/KCNB1

potassium voltage-gated channel subfamily B member 1 (KCNB1), potassium voltage-gated channel, Shab-related subfamily, member 1 (KCNB1), potassium channel, voltage gated Shab related subfamily B, member 1 (kcnb1), potassium voltage-gated channel subfamily B member 1 (LOC100541632), potassium voltage gated channel, Shab-related subfamily, member 1 (Kcnb1), potassium voltage-gated channel subfamily B member 1 (Kcnb1), DRK1, DRK1PC, h-DRK1, KCNB1, Kcnb1, Kcr1-1, Kv2.1, KV2.1, Shab

Protein level used designations for Kv2.1/KCNB1

  • Voltage-gated potassium channel subunit Kv2.1
  • potassium voltage-gated channel subfamily B member 1
  • potassium voltage-gated channel, Shab-related subfamily, member 1
  • voltage gated potassium channel subtype 2.1
  • potassium voltage-gated channel subfamily B member 1-like
  • delayed rectifier potassium channel 1
  • voltage-gated potassium channel subunit Kv2.1
  • DRK1
  • potassium channel Kv2.1
  • delayed rectifier potassium channel Kv2.1
  • h-DRK1 K(+) channel
  • potassium channel protein DRK1
  • voltage-gated potassium channel Kv2.1
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