Kv1.4 Products
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))
Categories
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011].
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Featured Kv1.4 Categories
Kv1.4 Antibodies
High quality antibodies with extensive validation data.
Kv1.4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Kv1.4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF, IHC, ICC, LCI
Validations
- (4)
Cat. No.
ABIN7043526
Quantity
25 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN1881472
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN517307
Quantity
50 μL
Datasheet
Datasheet
Recommended Kv1.4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969457
Quantity
96 tests
Datasheet
Datasheet
Recommended Kv1.4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308390
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3113175
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135408
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Kv1.4 products
: "Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus." in: Psychopharmacology, Vol. 232, Issue 11, pp. 1995-2006, (2015) (PubMed).: "N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity." in: Molecular brain, Vol. 8, pp. 4, (2015) (PubMed).
: "Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons." in: Molecular pain, Vol. 10, pp. 8, (2014) (PubMed).
: "Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability." in: Genes, brain, and behavior, Vol. 13, Issue 4, pp. 394-408, (2014) (PubMed).
: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).
: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." in: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).
: "Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage." in: PLoS ONE, Vol. 8, Issue 3, pp. e57808, (2013) (PubMed).
: "A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons." in: Nature neuroscience, Vol. 16, Issue 8, pp. 1024-31, (2013) (PubMed).
: "Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses." in: Journal of neurophysiology, Vol. 110, Issue 8, pp. 1751-64, (2013) (PubMed).
: "K+ channel alterations in the progression of experimental autoimmune encephalomyelitis." in: Neurobiology of disease, Vol. 47, Issue 2, pp. 280-93, (2012) (PubMed).
Synonyms and alternative names related to Kv1.4
potassium voltage-gated channel subfamily A member 4 (KCNA4), potassium voltage-gated channel subfamily A member 4 (LOC100622932), potassium voltage-gated channel subfamily A member 4 S homeolog (kcna4.S), potassium voltage-gated channel subfamily A member 4 (Kcna4), potassium voltage-gated channel, shaker-related subfamily, member 4 (Kcna4), DKFZp459N0126, HBK4, HK1, HPCN2, HUKII, KCHAN, KCNA4, KCNA4L, KCNA8, KV1.4, Kv1.4, Kv4, PCN2, RHK1, RK3Protein level used designations for Kv1.4
- Kv1.4 voltage-gated potassium channel
- potassium channel alpha subunit Kv1.4
- potassium voltage-gated channel, shaker-related subfamily, member 4
- potassium channel Shaker alpha subunit variant cKv1.4(m)
- Kv1.4 potassium channel
- RCK4
- potassium voltage gated channel, shaker related subfamily, member 4
- potassium voltage-gated channel subfamily A member 4
- voltage-gated potassium channel subunit Kv1.4
- cardiac potassium channel
- fetal skeletal muscle potassium channel
- potassium channel 2
- rapidly inactivating potassium channel
- shaker-related potassium channel Kv1.4
- type A potassium channel
- voltage-gated K(+) channel HuKII
- voltage-gated potassium channel HBK4
- voltage-gated potassium channel HK1
- BAK4
- potassium voltage-gated channel, shaker-related subfamily, memeber 4
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