KSR2 Products
(Kinase Suppressor of Ras 2 (KSR2))
Categories
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
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Featured KSR2 Categories
KSR2 Antibodies
High quality antibodies with extensive validation data.
KSR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
KSR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KSR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, RNAi
Validations
- (2)
- (5)
Cat. No.
ABIN567007
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (4)
Cat. No.
ABIN567001
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN655390
Quantity
400 μL
Datasheet
Datasheet
Recommended KSR2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968126
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968125
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648118
Quantity
96 tests
Datasheet
Datasheet
Recommended KSR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309084
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309083
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508983
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our KSR2 products
: "KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation. ..." in: Cell, Vol. 155, Issue 4, pp. 765-77, (2013) (PubMed).: "Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK." in: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3718-31, (2012) (PubMed).
: "Kinase suppressor of Ras 2 is involved in regulation of cell proliferation and is up-regulated in human invasive ductal carcinomas of breast." in: Experimental oncology, Vol. 32, Issue 3, pp. 209-12, (2011) (PubMed).
: "1,25-dihydroxyvitamin D3 enhances the apoptotic activity of MDM2 antagonist nutlin-3a in acute myeloid leukemia cells expressing wild-type p53." in: Molecular cancer therapeutics, Vol. 9, Issue 5, pp. 1158-68, (2010) (PubMed).
: "KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity." in: Cell metabolism, Vol. 10, Issue 5, pp. 366-78, (2009) (PubMed).
Synonyms and alternative names related to KSR2
kinase suppressor of ras 2 (KSR2), kinase suppressor of ras 2 (Ksr2)Protein level used designations for KSR2
- kinase suppressor of Ras 2
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