KRIT1 Products
(KRIT1, Ankyrin Repeat Containing (KRIT1))
Categories
This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009].
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Featured KRIT1 Categories
KRIT1 Antibodies
High quality antibodies with extensive validation data.
KRIT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KRIT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (3)
Cat. No.
ABIN1387606
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (2)
Cat. No.
ABIN7157699
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN560207
Quantity
50 μL
Datasheet
Datasheet
Recommended KRIT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123697
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308947
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308946
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our KRIT1 products
: "CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis." in: Human molecular genetics, Vol. 14, Issue 17, pp. 2521-31, (2005) (PubMed).Synonyms and alternative names related to KRIT1
KRIT1, ankyrin repeat containing (KRIT1), KRIT1, ankyrin repeat containing (Krit1), KRIT1, ankyrin repeat containing (krit1), 2010007K12Rik, A630036P20Rik, AA432855, AI450393, AI643869, BB155247, BB235701, CAM, CCM1, Ccm1, fb36f07, krit1, RGD1305929, san, santa, wu:fb36f07, zgc:63585Protein level used designations for KRIT1
- ankyrin repeat-containing protein Krit1
- cerebral cavernous malformations 1 protein
- krev interaction trapped 1
- krev interaction trapped protein 1
- cerebral cavernous malformations 1 protein homolog
- Krev interaction trapped protein 1
- ccm1
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