KPNA6 Products
(Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
Categories
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008].
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Featured KPNA6 Categories
KPNA6 Antibodies
High quality antibodies with extensive validation data.
KPNA6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KPNA6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7156132
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN263210
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN5675539
Quantity
100 μL
Datasheet
Datasheet
Recommended KPNA6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228950
Quantity
96 tests
Datasheet
Datasheet
Recommended KPNA6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308926
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422280
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093154
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KPNA6 products
: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." in: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).: "Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements." in: Cellular signalling, Vol. 18, Issue 8, pp. 1117-26, (2006) (PubMed).
Synonyms and alternative names related to KPNA6
karyopherin subunit alpha 6 (KPNA6), karyopherin (importin) alpha 6 (Kpna6), karyopherin alpha 6 (importin alpha 7) (KPNA6), karyopherin subunit alpha 6 (Kpna6), karyopherin alpha 6 (importin alpha 7) S homeolog (kpna6.S), IPOA7, Kpna5, KPNA7, NPI-2Protein level used designations for KPNA6
- karyopherin alpha 6 (importin alpha 7)
- importin subunit alpha-7-like
- importin alpha-S2
- importin subunit alpha-7
- karyopherin (importin) alpha 5
- karyopherin subunit alpha-6
- importin alpha 7 subunit
- importin-alpha-S2
- karyopherin (importin) alpha 6
- imp alpha 5
- importin alpha 5.2 protein
- Importin subunit alpha-7
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