KPNA4 Products
(Karyopherin (Importin) alpha 4 (KPNA4))
Categories
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008].
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Featured KPNA4 Categories
KPNA4 Antibodies
High quality antibodies with extensive validation data.
KPNA4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KPNA4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN185160
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (24)
Cat. No.
ABIN3015855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7156122
Quantity
100 μg
Datasheet
Datasheet
Recommended KPNA4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229027
Quantity
96 tests
Datasheet
Datasheet
Recommended KPNA4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308922
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423609
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2724406
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our KPNA4 products
: "A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration." in: Brain : a journal of neurology, Vol. 141, Issue 10, pp. 2908-2924, (2019) (PubMed).: "Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action." in: European journal of medicinal chemistry, Vol. 178, pp. 636-647, (2019) (PubMed).
: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).
: "Inhibition of KPNA4 attenuates prostate cancer metastasis." in: Oncogene, Vol. 36, Issue 20, pp. 2868-2878, (2017) (PubMed).
: "Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation." in: Journal of cell science, Vol. 128, Issue 12, pp. 2287-301, (2015) (PubMed).
: "Identification of a novel nuclear localization signal of baculovirus late expression factor 11." in: Virus research, Vol. 184, pp. 111-9, (2014) (PubMed).
: "Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2710-3, (2011) (PubMed).
: "Notch1 signaling is mediated by importins alpha 3, 4, and 7." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 18, pp. 3187-96, (2010) (PubMed).
: "Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8650-63, (2010) (PubMed).
: "Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression." in: Molecular biology of the cell, Vol. 20, Issue 20, pp. 4412-23, (2009) (PubMed).
Synonyms and alternative names related to KPNA4
karyopherin subunit alpha 4 (KPNA4), ARM repeat superfamily protein (MOS6), importin alpha 3 (LOC100533341), karyopherin (importin) alpha 4 (Kpna4), karyopherin subunit alpha 4 (Kpna4), karyopherin alpha 4 (importin alpha 3) S homeolog (kpna4.S), karyopherin alpha 4 (importin alpha 3) (kpna4), 6, 1110058D08Rik, ATIMPALPHA3, IMPA-3, impa3, importin, IMPORTIN ALPHA 3, IMPORTIN ALPHA ISOFORM 3, IPOA3, ipoa3, LOC100224013, MODIFIER OF SNC1, QIP1, qip1, SRP3, srp3, T10M13.16, T10M13_16, wu:fa56d07, wu:fa66g10, wu:fe14c04, wu:fi04h11, wu:fi19b05Protein level used designations for KPNA4
- importin alpha Q1
- importin subunit alpha-3
- importin subunit alpha-4
- karyopherin subunit alpha-4
- importin alpha 3
- karyopherin alpha 4 (importin alpha 3)
- qip1
- karyopherin (importin) alpha 4
- predicted role in nuclear import
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