KPNA3 Products
(Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
Categories
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. [provided by RefSeq, Jan 2009].
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Featured KPNA3 Categories
KPNA3 Antibodies
High quality antibodies with extensive validation data.
KPNA3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KPNA3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
- (7)
Cat. No.
ABIN6142991
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, FACS
Validations
- (3)
- (3)
Cat. No.
ABIN185159
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN625982
Quantity
50 μg
Datasheet
Datasheet
Recommended KPNA3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308920
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417918
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2724405
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our KPNA3 products
: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
: "Inhibition of spinal 5-HT3R reverted diabetes-induced mechanical hypersensitivity in a GABAAR-mediated neurotransmission-dependent manner." in: Neuroscience, Vol. 304, pp. 228-39, (2016) (PubMed).
: "Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway." in: Molecular cancer, Vol. 14, pp. 55, (2015) (PubMed).
: "mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3." in: Nature communications, Vol. 6, pp. 8192, (2015) (PubMed).
: "Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1226-9, (2015) (PubMed).
: "EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis." in: The Journal of pathology, Vol. 232, Issue 3, pp. 308-18, (2014) (PubMed).
: "PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis." in: Journal of hepatology, Vol. 59, Issue 1, pp. 105-13, (2013) (PubMed).
: "Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1." in: Carcinogenesis, Vol. 33, Issue 10, pp. 1854-62, (2012) (PubMed).
: "Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin ?." in: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 697-702, (2011) (PubMed).
Synonyms and alternative names related to KPNA3
karyopherin (importin) alpha 3 (Kpna3), karyopherin alpha 3 (importin alpha 4) (kpna3), karyopherin subunit alpha 3 (Kpna3), karyopherin subunit alpha 3 (KPNA3), karyopherin alpha 3 (importin alpha 4) L homeolog (kpna3.L), hSRP1, importin, IPOA4, ipoa4, si:dz79f24.2, SRP1, srp1, SRP1gamma, srp1gamma, SRP4, srp4Protein level used designations for KPNA3
- importin alpha Q2
- importin subunit alpha-3
- importin subunit alpha-4
- karyopherin subunit alpha-3
- qip2
- karyopherin alpha
- karyopherin (importin) alpha 3
- predicted role in nuclear import
- SRP1-gamma
- importin alpha 4
- importin alpha-3
- importin-alpha-Q2
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