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KPNA3 Products

(Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

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The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. [provided by RefSeq, Jan 2009].

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Featured KPNA3 Categories

KPNA3 Antibodies

High quality antibodies with extensive validation data.

KPNA3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KPNA3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
  • (7)
Cat. No. ABIN6142991
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, FACS
Validations
  • (3)
  • (3)
Cat. No. ABIN185159
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN625982
Quantity 50 μg
Datasheet Datasheet

Recommended KPNA3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308920
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417918
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724405
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our KPNA3 products

Li, Lu, Huang, Lv: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).

Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

Silva, Martins, Tavares, Morgado: "Inhibition of spinal 5-HT3R reverted diabetes-induced mechanical hypersensitivity in a GABAAR-mediated neurotransmission-dependent manner." in: Neuroscience, Vol. 304, pp. 228-39, (2016) (PubMed).

Zhang, Yang, Ma, Ingram, Lazar, Torres, Pollock: "Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway." in: Molecular cancer, Vol. 14, pp. 55, (2015) (PubMed).

Gebhardt, Habjan, Benda, Meiler, Haas, Hein, Mann, Mann, Habermann, Pichlmair: "mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3." in: Nature communications, Vol. 6, pp. 8192, (2015) (PubMed).

Jovičić, Mertens, Boeynaems, Bogaert, Chai, Yamada, Paul, Sun, Herdy, Bieri, Kramer, Gage, Van Den Bosch, Robberecht, Gitler: "Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1226-9, (2015) (PubMed).

Zhang, Garnett, Creighton, Al Sannaa, Igram, Lazar, Liu, Liu, Pollock: "EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis." in: The Journal of pathology, Vol. 232, Issue 3, pp. 308-18, (2014) (PubMed).

Méndez-Lucas, Duarte, Sunny, Satapati, He, Fu, Bermúdez, Burgess, Perales: "PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis." in: Journal of hepatology, Vol. 59, Issue 1, pp. 105-13, (2013) (PubMed).

Okazaki, Nakayama, Nariai, Nakayama, Miyazaki, Maruyama, Kato, Kosugi, Urano, Sakashita: "Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1." in: Carcinogenesis, Vol. 33, Issue 10, pp. 1854-62, (2012) (PubMed).

Ohara, Hata, Yasuhara, Mehmood, Yoneda, Nakagawa, Yamashita: "Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin ?." in: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 697-702, (2011) (PubMed).

Synonyms and alternative names related to KPNA3

karyopherin (importin) alpha 3 (Kpna3), karyopherin alpha 3 (importin alpha 4) (kpna3), karyopherin subunit alpha 3 (Kpna3), karyopherin subunit alpha 3 (KPNA3), karyopherin alpha 3 (importin alpha 4) L homeolog (kpna3.L), hSRP1, importin, IPOA4, ipoa4, si:dz79f24.2, SRP1, srp1, SRP1gamma, srp1gamma, SRP4, srp4

Protein level used designations for KPNA3

  • importin alpha Q2
  • importin subunit alpha-3
  • importin subunit alpha-4
  • karyopherin subunit alpha-3
  • qip2
  • karyopherin alpha
  • karyopherin (importin) alpha 3
  • predicted role in nuclear import
  • SRP1-gamma
  • importin alpha 4
  • importin alpha-3
  • importin-alpha-Q2
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