KPNA1 Products
(Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
Categories
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
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Featured KPNA1 Categories
KPNA1 Antibodies
High quality antibodies with extensive validation data.
KPNA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KPNA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (6)
Cat. No.
ABIN3022472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (5)
Cat. No.
ABIN561614
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (4)
Cat. No.
ABIN561613
Quantity
50 μL
Datasheet
Datasheet
Recommended KPNA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228951
Quantity
96 tests
Datasheet
Datasheet
Recommended KPNA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308914
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7405133
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093110
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KPNA1 products
: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).: "Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box." in: Biochemical and biophysical research communications, Vol. 462, Issue 3, pp. 201-7, (2015) (PubMed).
: "Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery." in: The FEBS journal, Vol. 278, Issue 9, pp. 1561-72, (2011) (PubMed).
: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." in: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).
: "Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 8984-94, (2008) (PubMed).
: "Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1164-78, (2007) (PubMed).
: "RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 16, pp. 7633-7, (1994) (PubMed).
Synonyms and alternative names related to KPNA1
karyopherin subunit alpha 1 (KPNA1), karyopherin subunit alpha 1 (Kpna1), importin alpha-1 subunit (EHI_124900), karyopherin (importin) alpha 1 (Kpna1), karyopherin alpha 1 (importin alpha 5) (kpna1), AW494490, IPOA5, mSRP1, NPI-1, NPI1, RCH2, Rch2, si:ch211-161h7.7, SRP1Protein level used designations for KPNA1
- RAG cohort protein 2
- SRP1-beta
- importin alpha 5
- importin subunit alpha-1
- importin subunit alpha-5
- importin-alpha-S1
- karyopherin subunit alpha-1
- nucleoprotein interactor 1
- recombination activating gene cohort 2
- Importin subunit alpha-1
- importin alpha-5
- karyopherin (importin) alpha 1
- karyopherin/importin alpha-1
- importin alpha-1 subunit
- NPI-1
- importin alpha-S1
- m-importin-alpha-S1
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