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KNSTRN Products

(Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

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Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments (By similarity).

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Featured KNSTRN Categories

KNSTRN Antibodies

High quality antibodies with extensive validation data.

KNSTRN Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KNSTRN Antibodies

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Reactivity Human
Application WB
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Cat. No. ABIN7233849
Quantity 200 μL
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Cat. No. ABIN6750719
Quantity 100 μL
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Cat. No. ABIN6750720
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Recommended KNSTRN Proteins

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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
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  • (1)
Cat. No. ABIN2718579
Quantity 20 μg
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Reactivity Human
Source HEK-293T Cells
Validations
  • (1)
Cat. No. ABIN2718580
Quantity 20 μg
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Latest Publications for our KNSTRN products

Tamura, Simon, Nayak, Shenoy, Hiroi, Boilot, Funahashi, Draviam: "A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset." in: Biology open, Vol. 4, Issue 2, pp. 155-69, (2015) (PubMed).

Shrestha, Draviam: "Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK." in: Current biology : CB, Vol. 23, Issue 16, pp. 1514-26, (2013) (PubMed).

Synonyms and alternative names related to KNSTRN

kinetochore-localized astrin/SPAG5 binding (Knstrn), kinetochore localized astrin/SPAG5 binding protein (KNSTRN), kinetochore-localized astrin/SPAG5 binding protein (Knstrn), 1700025D04Rik, C15orf23, D2Ertd750e, SKAP, Traf4af1, TRAF4AF1

Protein level used designations for KNSTRN

  • TRAF4 associated factor 1 homolog
  • TRAF4-associated factor 1
  • kinastrin
  • kinetochore-localized astrin-binding protein
  • kinetochore-localized astrin/SPAG5-binding protein
  • putative TRAF4-associated factor 1
  • small kinetochore-associated protein
  • TRAF4 associated factor 1
  • small kinetochore associated protein
  • small kinetochore-associated protein, kinetochore-localized astrin-binding protein, TRAF4 associated factor 1
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