KLRC2 Products
(Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Featured KLRC2 Categories
KLRC2 Antibodies
High quality antibodies with extensive validation data.
KLRC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KLRC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN652570
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7440197
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7161641
Quantity
100 μg
Datasheet
Datasheet
Recommended KLRC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN417112
Quantity
96 tests
Datasheet
Datasheet
Recommended KLRC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275345
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275336
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275341
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KLRC2 products
: "NKG2C(+)CD57(+) Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8(+) T Cell Evolution towards Senescence." in: Journal of immunology research, Vol. 2016, pp. 7470124, (2016) (PubMed).: "KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells." in: European journal of immunology, Vol. 46, Issue 1, pp. 185-91, (2016) (PubMed).
: "CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection." in: European journal of immunology, Vol. 46, Issue 10, pp. 2420-2425, (2016) (PubMed).
: "Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 1, pp. 313-25, (2016) (PubMed).
: "Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005788, (2016) (PubMed).
: "New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells." in: Journal of leukocyte biology, Vol. 100, Issue 3, pp. 471-9, (2016) (PubMed).
: "Association of high HLA-E expression during acute cellular rejection and numbers of HLA class I leader peptide mismatches with reduced renal allograft survival." in: Immunobiology, Vol. 222, Issue 3, pp. 536-543, (2016) (PubMed).
: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, (2015) (PubMed).
: "Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 10, pp. 4657-67, (2015) (PubMed).
: "Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3513-25, (2015) (PubMed).
Synonyms and alternative names related to KLRC2
killer cell lectin like receptor C2 (KLRC2), killer cell lectin-like receptor subfamily C, member 2 (KLRC2), CD159c, NKG2-C, NKG2CProtein level used designations for KLRC2
- CD159 antigen-like family member C
- NK cell receptor C
- NKG2-C type II integral membrane protein
- NKG2-C-activating NK receptor
- NKG2-FE
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