Klotho Products
(Klotho (KL))
Categories
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008].
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Featured Klotho Categories
Klotho Antibodies
High quality antibodies with extensive validation data.
Klotho ELISA Kits
Reliable ELISA kits for a wide range of species.
Klotho Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Klotho Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7436549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC (p), IHC (fro), IF (p)
Validations
- (1)
- (4)
Cat. No.
ABIN681778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7436552
Quantity
100 μL
Datasheet
Datasheet
Recommended Klotho ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (6)
Cat. No.
ABIN6730981
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN6957334
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957335
Quantity
96 tests
Datasheet
Datasheet
Recommended Klotho Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505805
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
CHO Cells
Validations
Cat. No.
ABIN935600
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400465
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Klotho products
: "The use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats." in: Expert opinion on therapeutic targets, Vol. 23, Issue 4, pp. 353-364, (2020) (PubMed).: "P2X7 siRNA targeted to the kidneys increases klotho and delays the progression of experimental diabetic nephropathy." in: Purinergic signalling, Vol. 16, Issue 2, pp. 175-185, (2020) (PubMed).
: "Klotho ameliorates the onset and progression of cataract via suppressing oxidative stress and inflammation in the lens in streptozotocin-induced diabetic rats." in: International immunopharmacology, Vol. 85, pp. 106582, (2020) (PubMed).
: "Expression of α-Klotho Is Downregulated and Associated with Oxidative Stress in the Lens in Streptozotocin-induced Diabetic Rats." in: Current eye research, pp. 1-8, (2020) (PubMed).
: "Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats." in: Scientific reports, Vol. 7, Issue 1, pp. 10830, (2019) (PubMed).
: "Is there a role for newer biomarkers in chronic kidney disease-mineral and bone disorder management?" in: Nephrology (Carlton, Vic.), Vol. 22 Suppl 2, pp. 14-18, (2018) (PubMed).
: "Changes of Klotho protein and Klotho mRNA expression in a hydroxy-L-proline induced hyperoxaluric rat model." in: The Journal of veterinary medical science, Vol. 79, Issue 11, pp. 1861-1869, (2018) (PubMed).
: "Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration." in: Nature communications, Vol. 9, Issue 1, pp. 4859, (2018) (PubMed).
: "Klotho Reduces Necroptosis by Targeting Oxidative Stress Involved in Renal Ischemic-Reperfusion Injury." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 6, pp. 2268-2282, (2018) (PubMed).
: "Advanced maternal age impairs spatial learning capacity in young adult mouse offspring." in: American journal of translational research, Vol. 10, Issue 3, pp. 975-988, (2018) (PubMed).
Synonyms and alternative names related to Klotho
klotho (KL), klotho (Kl), Klotho (Kl), klotho (kl), klotho (LOC100533542), alpha-kl, KL, LOC100223456Protein level used designations for Klotho
- secreted form of Klotho protein
- klotho
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