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KLLN Products

(Killin, p53-Regulated DNA Replication Inhibitor (KLLN))

Categories

DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA.

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Featured KLLN Categories

KLLN Antibodies

High quality antibodies with extensive validation data.

Recommended KLLN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN655558
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7001371
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IHC (p)
Validations
Cat. No. ABIN872503
Quantity 100 μL
Datasheet Datasheet

Recommended KLLN Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3082705
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KLLN products

Wang, Roma, Nolley, Abdul-Karim, Peehl, Eng: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).

Wang, Yu, He, Romigh, Altemus, Eng: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." in: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).

Wang, He, Yu, Eng: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).

Synonyms and alternative names related to KLLN

killin, p53-regulated DNA replication inhibitor (KLLN), CWS4, KILLIN

Protein level used designations for KLLN

  • killin
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