KLKB1 Products
(Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
Categories
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq, Jul 2008].
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Featured KLKB1 Categories
KLKB1 Antibodies
High quality antibodies with extensive validation data.
KLKB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
KLKB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KLKB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6262852
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7256830
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7187793
Quantity
100 μg
Datasheet
Datasheet
Recommended KLKB1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6976253
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6976057
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975157
Quantity
96 tests
Datasheet
Datasheet
Recommended KLKB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275096
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275094
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275098
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KLKB1 products
: "Proteomic analysis of serum from patients with major depressive disorder to compare their depressive and remission statuses." in: Psychiatry investigation, Vol. 12, Issue 2, pp. 249-59, (2015) (PubMed).: "Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 41077-89, (2005) (PubMed).
Synonyms and alternative names related to KLKB1
kallikrein B1 (KLKB1), kallikrein B, plasma 1 (Klkb1), kallikrein B1 (Klkb1), plasma kallikrein (CpipJ_CPIJ004042), plasma kallikrein (CpipJ_CPIJ014955), plasma kallikrein (CpipJ_CPIJ020108), Plasma kallikrein (VAA_02266), kallikrein B, plasma (Fletcher factor) 1 (KLKB1), coagulation factor XI (LOC100549617), kallikrein B1 (klkb1), kallikrein B1 L homeolog (klkb1.L), APS, DKFZp459J2015, Kal-3, Kal3, Kalp1, KALP15, KLK3, Klk3, KLKB1, klkb1, PPK, PSAProtein level used designations for KLKB1
- Fletcher factor
- kininogenin
- plasma kallikrein
- plasma kallikrein heavy chain
- plasma kallikrein light chain
- plasma prekallikrein
- antigen, prostate specific
- fletcher factor
- kallikrein 3, plasma
- kallikrein B, plasma (Fletcher factor) 1
- Plasma kallikrein
- plasma kallikrein-like
- plasma kallikrein B1
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