KLHL3 Products
(Kelch-Like 3 (KLHL3))
Categories
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)\; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
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Featured KLHL3 Categories
KLHL3 Antibodies
High quality antibodies with extensive validation data.
KLHL3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KLHL3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7184471
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6262847
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7157290
Quantity
100 μg
Datasheet
Datasheet
Recommended KLHL3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229034
Quantity
96 tests
Datasheet
Datasheet
Recommended KLHL3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308817
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1793163
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3082516
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KLHL3 products
: "Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 19, pp. 7838-43, (2013) (PubMed).Synonyms and alternative names related to KLHL3
kelch like family member 3 (KLHL3), kelch-like 3 (Klhl3), kelch-like family member 3 (Klhl3), 7530408C15Rik, AI430941, EG627648, PHA2D, RGD1565218Protein level used designations for KLHL3
- kelch-like protein 3
- kelch-like 3
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