KLF1 Products
(Kruppel-Like Factor 1 (erythroid) (KLF1))
Categories
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009].
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Featured KLF1 Categories
KLF1 Antibodies
High quality antibodies with extensive validation data.
KLF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
KLF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KLF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN1724828
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (4)
Cat. No.
ABIN184728
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (3)
Cat. No.
ABIN524111
Quantity
100 μg
Datasheet
Datasheet
Recommended KLF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957337
Quantity
96 tests
Datasheet
Datasheet
Recommended KLF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308729
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308727
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397447
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KLF1 products
: "Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3)." in: The Journal of biological chemistry, Vol. 290, Issue 15, pp. 9929-40, (2015) (PubMed).: "TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8592-604, (2014) (PubMed).
: "Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis." in: PLoS ONE, Vol. 5, Issue 12, pp. e15358, (2011) (PubMed).
: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).
: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).
: "EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation." in: Molecular and cellular biology, Vol. 30, Issue 11, pp. 2811-22, (2010) (PubMed).
: "Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1510-7, (2010) (PubMed).
: "Distinct modes of gene regulation by a cell-specific transcriptional activator." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4213-8, (2009) (PubMed).
: "CTCF-dependent enhancer-blocking by alternative chromatin loop formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 51, pp. 20398-403, (2008) (PubMed).
: "Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16304-12, (2002) (PubMed).
Synonyms and alternative names related to KLF1
Kruppel-like factor 1 (erythroid) (KLF-4), Kruppel like factor 1 (KLF1), Kruppel-like factor 1 (erythroid) (Klf1), Kruppel like factor 1 (Klf1), EKLF, Eklf, HBFQTL6, INLU, KLF1, NanProtein level used designations for KLF1
- Kruppel-like factor 1 (erythroid)
- Krueppel-like factor 1
- erythroid Kruppel-like factor
- erythroid krueppel-like transcription factor
- erythroid-specific transcription factor EKLF
- monoclonal antibody A3D8
- erythroid transcription factor
- neonatal anemia
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