HEV Ab ELISA Kit

Catalog No. ABIN997026

Product Details HEV Ab ELISA Kit

Target: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Reactivity: Hepatitis E Virus (HEV)

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: ELISA KIT FOR TOTAL ANTIBODIES TO HEPATITIS E VIRUS Two-Step Incubation, Double Antigen Sandwich Principle

Sample Type: Serum

Analytical Method: Qualitative

Specificity: 99.60%

Sensitivity: 99.80%

Application Details

Sample Volume: 50 μL

Assay Time: 1 - 2 h

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Expiry Date: 12-18 months

Target Details for HEV Ab

Target: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Alternative Name: HEV Ab

Background: Hepatitis E virus (HEV) is a non-enveloped, single- stranded RNA virus identified in 1990. Infection with HEV induces acute or sub-clinical liver diseases similar to hepatitis A. HEV infections, endemic and frequently epidemic in developing countries, is seen also in developed countries in a sporadic form with or without a history of traveling to endemic area. The overall case-fatality is 0.5~3%, and much higher (15~25%) among pregnant women. A hypothesis that HEV infection is a zoonosis was presented in 1995. Then a swine HEV and later an avian HEV were identified and sequenced separately in 1997 and 2001. Since then, HEV infection include anti-HEV, viremia and feces excretion of HEV was seen in a wide variety of animals, i.e., swine, rodents, wild monkeys, deer, cow, goats, dogs and chicken in both the developing and developed countries. A direct testimony was reported that the consumption of uncooked dear meat contaminated with HEV led to acute hepatitis E in human, and HEV genome sequences can be detected in pork livers available in the supermarkets in Japan. With the discovery of conformational epitopes in HEV, HEV serology was further explored and understood. The phenomenon of long-lasting and protective antibodies to HEV was observed which greatly enhance the understanding to the diagnosis, epidemiology, zoonosis-related studies and vaccine development.