HSV1 IgA
(Anti-Herpes Simplex Virus Type 1 IgA (HSV1 IgA))
Reactivity
Herpes Simplex Virus (HSV)
Detection Method
Colorimetric
Method Type
Competition ELISA
Application
ELISA
Purpose
ELISA, HSV 1 IgA is intended for the detection of IgA antibodies to herpes simplex virus 1 (HSV 1).
Sample Type
Serum
Analytical Method
Qualitative
Specificity
98.70%
Sensitivity
98%
Sample Volume
5 μL
Assay Time
1 - 2 h
Plate
Pre-coated
Restrictions
For Research Use only
Storage
4 °C
Expiry Date
12-18 months
Target
HSV1 IgA
(Anti-Herpes Simplex Virus Type 1 IgA (HSV1 IgA))
Alternative Name
Herpes Simplex 1 IgA (HSV1 IgA)
Target Type
Antibody, Antibody
Background
Herpes Simplex Virus is a common pathogen and its primary infection is usually asymptomatic. There are two immunologically distinct types of HSV: Type 1 and Type 2. HSV 1 is generally associated with oral infection and lesions above the waist, and HSV 2 is associated with genital infections and lesions below the waist. Clinical cases primarily are 1) eczema herpeticum with eczematous skin changes with numerous lesions, 2) Gingivo-stomatitis and 3) Herpes sepsis, almost only found in newly born of premature infants. The antibodies present to HSV 1 may be of the IgA, IgM and IgG isotypes. The physiological function of IgA and its clinical implication is still unclear.