CMV IgM ELISA Kit
CMV IgM
Reactivity: Cytomegalovirus (CMV)
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- Target See all CMV IgM products
- CMV IgM (Anti-Cytomegalovirus IgM Antibody (CMV IgM))
- Reactivity
- Cytomegalovirus (CMV)
- Application
- ELISA
- Characteristics
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ELISA kit for the detection of CMV IgM in the research laboratory
Alternative Names: Cytomegalovirus IgM ELISA kit
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- Application Notes
- Optimal conditions to be determined by end user
- Assay Procedure
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Diluted patient serum (serum diluent contains sorbent to remove Rheumatoid Factor and human lgG interference) is added to wells coated with purified antigen. 1gM specific antibody, if present, binds to the antigen. All unbound materials are washed away and the enzyme conjugate is added to bind to the antibodyantigen complex, if present. Excess enzyme conjugate is washed off and substrate is added. The plate is incubated to allow the hydrolysis of the substrate by the enzyme. The intensity of the color generated is proportional to the amount of 1gM specific antibody in the sample.
- Restrictions
- For Research Use only
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- Storage
- 4 °C
- Storage Comment
- Store at 2-8 °C.
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- Target See all CMV IgM products
- CMV IgM (Anti-Cytomegalovirus IgM Antibody (CMV IgM))
- Alternative Name
- Anti-CMV IgM (CMV IgM Products)
- Target Type
- Antibody, Antibody
- Background
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Cytomegalovirus (CMV) is a member of the herpes group of viruses. Most adults and children who catch CMV have no symptoms and are not harmed by the virus. CMV infection is of clinical significance primarily in pregnant women, newborn infants with possible congenital infection, immunosuppressed transplant patients and individuals with AIDS. CMV is so prevalent as over 60 % of people catch the infection at some time in their lives. Significant increases in CMV lgG antibody by ELISA suggest recent infection or reactivation of a latent CMV infection. CMV IgM antibody can be detected by ELISA in both primary CMV infections (93-100 %) and in reactivated infection (40 %). An IgM response may be reduced or absent in immunocompromised patients with active infection. In transplant patients the CMV infection can be associated with higher morbidity and mortality.
Synonyms: Cytomegalovirus IgM ELISA kit.
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