Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

FURIN ELISA Kit

FURIN Reactivity: Human Colorimetric Sandwich ELISA 312 pg/mL - 20000 pg/mL Cell Culture Lysate, Cell Culture Supernatant, Tissue Homogenate
Catalog No. ABIN6720393
  • Target See all FURIN ELISA Kits
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    Reactivity
    • 6
    • 2
    • 1
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    312 pg/mL - 20000 pg/mL
    Minimum Detection Limit
    312 pg/mL
    Application
    ELISA
    Purpose
    Sandwich ELISA for Quantitative Detection of Antigen
    Sample Type
    Cell Culture Lysate, Cell Culture Supernatant, Tissue Homogenate
    Analytical Method
    Quantitative
    Characteristics

    Synonyms: Dibasic processing enzyme, Dibasic-processing enzyme, FES upstream region, FUR, FURIN, Furin membrane associated receptor protein, FURIN_HUMAN, PACE, Paired basic amino acid residue cleaving enzyme, Paired basic amino acid residue-cleaving enzyme, PCSK3, Proprotein convertase subtilisin/kexin type 3, SPC1

    Background: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance

    Gene Name: FURIN

    Production: Natural and recombinant human Furin. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: D108-E715

    Top Product
    Discover our top product FURIN ELISA Kit
  • Application Notes

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20000pg/mL, 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human Furin standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, tissue homogenates or cell lysates to each empty well. It is recommended that each human Furin standard solution and each sample be measured in duplicate.

    ELISA Dilution: 312pg/mL-20000pg/mL

    Sample Volume
    100 μL
    Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    RT,4 °C,-20 °C
    Storage Comment
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Target See all FURIN ELISA Kits
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    Alternative Name
    Furin (FURIN Products)
    Synonyms
    FURIN ELISA Kit, furin ELISA Kit, si:dkey-281a24.5 ELISA Kit, FUR ELISA Kit, LOC100220259 ELISA Kit, PACE ELISA Kit, spc1 ELISA Kit, xfurin ELISA Kit, MGC82710 ELISA Kit, PCSK3 ELISA Kit, SPC1 ELISA Kit, 9130404I01Rik ELISA Kit, Fur ELISA Kit, Pcsk3 ELISA Kit, Pace ELISA Kit, furin, paired basic amino acid cleaving enzyme ELISA Kit, furin (paired basic amino acid cleaving enzyme) a ELISA Kit, furin (paired basic amino acid cleaving enzyme) b ELISA Kit, furin, paired basic amino acid cleaving enzyme L homeolog ELISA Kit, furin (paired basic amino acid cleaving enzyme) ELISA Kit, FURIN ELISA Kit, furina ELISA Kit, furinb ELISA Kit, furin ELISA Kit, furin.L ELISA Kit, Furin ELISA Kit
    Gene ID
    5045
    NCBI Accession
    NP_001276752
    UniProt
    P09958
    Pathways
    Notch Signaling, Neurotrophin Signaling Pathway
You are here:
Support