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CYR61 ELISA Kit

CYR61 Reactivity: Human Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Breast Milk, Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine
Catalog No. ABIN6720366
  • Target See all CYR61 ELISA Kits
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Reactivity
    • 8
    • 4
    • 1
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    31.2 pg/mL - 2000 pg/mL
    Minimum Detection Limit
    31.2 pg/mL
    Application
    ELISA
    Purpose
    Sandwich ELISA for Quantitative Detection of Antigen
    Sample Type
    Breast Milk, Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine
    Analytical Method
    Quantitative
    Characteristics

    Synonyms: 3CH61, CCN 1, CCN family member 1, CCN1, CCN1, CYR 61, Cyr61, CYR61 protein, CYR61 protein precursor, CYR61 protein precursor, CYR61_HUMAN, Cysteine rich angiogenic inducer 61, Cysteine rich heparin binding protein 61, Cysteine-rich angiogenic inducer 61, GIG 1, GIG1, GIG1 protein, IBP-10, IGF-binding protein 10, Igfbp 10, IGFBP-10, IGFBP10, Insulin like growth factor binding protein 10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1

    Background: Cysteine-rich angiogenic inducer 61(CYR61) or CCN family member 1(CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

    Gene Name: CYR61

    Production: Natural and recombinant human CYR61. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: CHO, Immunogen sequence: A22-D381

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    Discover our top product CYR61 ELISA Kit
  • Application Notes

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human CYR61 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA), saliva, urine or human milk to each empty well. It is recommended that each human CYR61 standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 31.2pg/mL-2000pg/mL

    Sample Volume
    100 μL
    Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    RT,4 °C,-20 °C
    Storage Comment
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Target See all CYR61 ELISA Kits
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Alternative Name
    CYR61 - CCN1 (CYR61 Products)
    Synonyms
    CCN1 ELISA Kit, GIG1 ELISA Kit, IGFBP10 ELISA Kit, ccn1 ELISA Kit, gig1 ELISA Kit, Xcyr61 ELISA Kit, igfbp10 ELISA Kit, MGC69281 ELISA Kit, MGC69539 ELISA Kit, cyr61-l2 ELISA Kit, zgc:158158 ELISA Kit, CYR61 ELISA Kit, AI325051 ELISA Kit, Igfbp10 ELISA Kit, cysteine rich angiogenic inducer 61 ELISA Kit, cysteine-rich, angiogenic inducer, 61 ELISA Kit, cysteine-rich, angiogenic inducer, 61 like 2 ELISA Kit, cysteine rich protein 61 ELISA Kit, cysteine rich angiogenic inducer 61 S homeolog ELISA Kit, CYR61 ELISA Kit, Cyr61 ELISA Kit, cyr61 ELISA Kit, cyr61l2 ELISA Kit, cyr61.S ELISA Kit
    Gene ID
    3491
    NCBI Accession
    NP_001545
    UniProt
    O00622
    Pathways
    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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