IL17RA ELISA Kit

Catalog No. ABIN6720172

Product Details IL17RA ELISA Kit

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 31.2 pg/mL - 2000 pg/mL

Minimum Detection Limit: 31.2 pg/mL

Application: ELISA

Purpose: Sandwich ELISA for Quantitative Detection of Antigen

Sample Type: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Characteristics:

Synonyms: CANDF5, CD217, CD217 antigen, CDw217, CTLA8, HIL 17R, I17RA_HUMAN, IL 17 receptor A, IL 17 receptor, IL 17RA, IL-17 receptor A, IL-17RA, IL17, IL17A receptor, IL17R, IL17RA, Interleukin 17 receptor A, Interleukin-17 receptor A, MGC10262

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Also, it is showed that mouse Il17r bound HSV-13 and mouse Il17. Recombinant soluble Il17r inhibited mitogen-induced T-cell proliferation and Il2 production.

Gene Name: IL17RA

Production: Natural and recombinant human IL-17RA. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: L33-W320

Application Details

Application Notes:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human IL-17RA standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum and plasma (heparin, EDTA) to each empty well. It is recommended that each human IL-17RA standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 31.2pg/mL-2000pg/mL

Sample Volume: 100 μL

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: RT,4 °C,-20 °C

Storage Comment: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL-17RA (IL17RA Products)

Synonyms: IL17R ELISA Kit, CANDF5 ELISA Kit, CD217 ELISA Kit, CDw217 ELISA Kit, IL-17RA ELISA Kit, hIL-17R ELISA Kit, Il17r ELISA Kit, AW538159 ELISA Kit, Cdw217 ELISA Kit, VDw217 ELISA Kit, interleukin 17 receptor A ELISA Kit, IL17RA ELISA Kit, Il17ra ELISA Kit

Gene ID: 23765

NCBI Accession: NP_001276834

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome