CD21 ELISA Kit
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- Target See all CD21 (CR2) ELISA Kits
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 0.78 ng/mL - 50 ng/mL
- Minimum Detection Limit
- 0.78 ng/mL
- Application
- ELISA
- Purpose
- Sandwich ELISA for Quantitative Detection of Antigen
- Sample Type
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Characteristics
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Synonyms: C3DR, CD 21, CD21, CD21 antigen, Complement C3d receptor, Complement component (3d/Epstein Barr virus) receptor 2, Complement component receptor 2, Complement receptor type 2, Cr 2, CR, Cr2, CR2_HUMAN, CVID7, EBV receptor, EBV-R, Epstein Barr virus receptor, Epstein-Barr virus receptor, EVBR, SLEB9
Background: Complement receptor type 2(CR2), also known as C3DR or CD21, is a protein that in humans is encoded by the CR2 gene. It is mapped to 1q32.2. CR2 is involved in the complement system. It binds to iC3b(inactive derivative of C3b), C3dg, or C3d. CR2 is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. CR2, together with CD19, CD81, and CD225, forms the B-cell coreceptor complex, which lowers the activation threshold of the B-cell antigen receptor. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).
Gene Name: CR2
Production: Natural and recombinant human CD21. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: CHO, Immunogen sequence: Ile21-71
- Top Product
- Discover our top product CR2 ELISA Kit
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- Application Notes
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 50 ng/mL, 25 ng/mL, 12.5 ng/mL, 6.25 ng/mL, 3.12 ng/mL, 1.56 ng/mL, 0.78 ng/mL human CD21 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human CD21 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 0.78 ng/mL-50 ng/mL
- Sample Volume
- 100 μL
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Target See all CD21 (CR2) ELISA Kits
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- Alternative Name
- CD21 - CR2 (CR2 Products)
- Synonyms
- C3DR ELISA Kit, CD21 ELISA Kit, CR ELISA Kit, CVID7 ELISA Kit, SLEB9 ELISA Kit, Cd21 ELISA Kit, cd21 ELISA Kit, CR1 ELISA Kit, CR1-L ELISA Kit, CR2 ELISA Kit, complement C3d receptor 2 ELISA Kit, complement C3b/C4b receptor 1 (Knops blood group) ELISA Kit, CR2 ELISA Kit, Cr2 ELISA Kit, CR1 ELISA Kit
- Gene ID
- 1380
- NCBI Accession
- NP_001006659
- UniProt
- P20023
- Pathways
- Complement System
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