DAND5 ELISA Kit

Catalog No. ABIN5692233

Product Details DAND5 ELISA Kit

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Binding Specificity: AA 23-189

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 62.5 pg/mL - 4000 pg/mL

Minimum Detection Limit: 62.5 pg/mL

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human DAND5. 96wells/kit, with removable strips.

Brand: PicoKine™

Sample Type: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Specificity: Expression system for standard: E.coli, Immunogen sequence: R23-A189

Sensitivity: < 10 pg/mL

Components: 96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover

Application Details

Assay Time: 15 min

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for DAND5

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Alternative Name: DAND5 (DAND5 Products)

Synonyms: CER2 ELISA Kit, CERL2 ELISA Kit, CKTSF1B3 ELISA Kit, COCO ELISA Kit, CRL2 ELISA Kit, DANTE ELISA Kit, GREM3 ELISA Kit, SP1 ELISA Kit, 51-B6 ELISA Kit, cer2 ELISA Kit, cerl2 ELISA Kit, cktsf1b3 ELISA Kit, coco ELISA Kit, crl2 ELISA Kit, dante ELISA Kit, grem3 ELISA Kit, xCoco ELISA Kit, Cerl-2 ELISA Kit, Cerr2 ELISA Kit, Dte ELISA Kit, DAN domain BMP antagonist family member 5 ELISA Kit, DAN domain family member 5, BMP antagonist S homeolog ELISA Kit, DAN domain family member 5, BMP antagonist ELISA Kit, DAND5 ELISA Kit, dand5.S ELISA Kit, Dand5 ELISA Kit

Background:

Synonyms: DAN domain family member 5, Cerberus-like protein 2, Cerl-2, Cysteine knot superfamily 1, BMP antagonist 3, Gremlin-3, DAND5, CER2, CKTSF1B3, GREM3, SP1

Background: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Cellular Localisation: Secreted.

UniProt: Q8N907