ARTN ELISA Kit
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- Target See all ARTN ELISA Kits
- ARTN (Artemin (ARTN))
- Binding Specificity
- AA 108-220
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 62.5 pg/mL - 4000 pg/mL
- Minimum Detection Limit
- 62.5 pg/mL
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Artemin. 96wells/kit, with removable strips.
- Brand
- PicoKine™
- Sample Type
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Specificity
- Expression system for standard: E.coli, Immunogen sequence: A108-G220
- Sensitivity
- < 2 pg/mL
- Components
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
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- Assay Time
- 15 min
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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- Target See all ARTN ELISA Kits
- ARTN (Artemin (ARTN))
- Alternative Name
- ARTN (ARTN Products)
- Synonyms
- ARTN ELISA Kit, ENOVIN ELISA Kit, EVN ELISA Kit, NBN ELISA Kit, neublastin ELISA Kit, artemin ELISA Kit, ARTN ELISA Kit, Artn ELISA Kit
- Background
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Synonyms: Artemin, Enovin, Neublastin, ARTN, EVN
Tissue Specificity: Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
Background: Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.
Cellular Localisation: Secreted. - UniProt
- Q5T4W7
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