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AZGP1 ELISA Kit

AZGP1 Reactivity: Human Colorimetric Sandwich ELISA 0.9375-60 ng/mL Cell Culture Supernatant, Plasma, Serum
Catalog No. ABIN5564198
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    AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
    Reactivity
    • 7
    • 4
    • 3
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    0.9375-60 ng/mL
    Minimum Detection Limit
    0.9375 ng/mL
    Application
    ELISA
    Sample Type
    Cell Culture Supernatant, Plasma, Serum
    Analytical Method
    Quantitative
    Specificity
    Detects human Zinc-alpha-2-glycoprotein.
    Cross-Reactivity
    Human
    No Cross-Reactivity
    Mouse (Murine)
    Cross-Reactivity (Details)
    Does not detect mouse Zinc-alpha-2-glycoprotein.
    Sensitivity
    0.23 ng/mL
    Characteristics
    Zinc-alpha-2-glycoprotein (human) TurboELISA Kit
    This assay is a less than 1 hour sandwich Enzyme Linked-Immunosorbent Assay (ELISA) for quantitative determination of human Zinc-alpha-2-glycoprotein in biological fluids. Zinc-alpha-2-glycoprotein (ZAG) was first identified in the 1960s, and it's name derives from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently, the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
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    Discover our top product AZGP1 ELISA Kit
  • Comment

    TRADEMARKS - TurboELISA™ and Turbo-coated Plate™ are Trademarks of Adipogen Life Sciences.

    Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: +4°C
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • Target See all AZGP1 ELISA Kits
    AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
    Alternative Name
    Zinc-alpha-2-glycoprotein (AZGP1 Products)
    Synonyms
    Zag ELISA Kit, ZA2G ELISA Kit, ZAG ELISA Kit, ZA2GA ELISA Kit, Zna2gp ELISA Kit, alpha-2-glycoprotein 1, zinc ELISA Kit, alpha-2-glycoprotein 1, zinc-binding ELISA Kit, Azgp1 ELISA Kit, AZGP1 ELISA Kit
    UniProt
    P25311
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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