TGFBI ELISA Kit

Catalog No. ABIN5510728

Product Details TGFBI ELISA Kit

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Binding Specificity: AA 24-685

Reactivity: Rat

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat beta IG-H3/TGFBI

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: G24-G685

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Highly expressed in the corneal epithelium. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for TGFBI

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Alternative Name: TGFBI (TGFBI Products)

Background:

Protein Function: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Background: Transforming growth factor, beta-induced, 68 kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. It is induced by transforming growth factor-beta and acts to inhibit cell adhesion.

Synonyms: Transforming growth factor-beta-induced protein ig-h3,Beta ig-h3,Kerato-epithelin,RGD-containing collagen-associated protein,RGD-CAP,TGFBI,BIGH3,

Full Gene Name: Transforming growth factor-beta-induced protein ig-h3

Cellular Localisation: Secreted, extracellular space, extracellular matrix. May be associated both with microfibrils and with the cell surface.

UniProt: Q15582