GDF2 ELISA Kit
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- Target See all GDF2 ELISA Kits
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Binding Specificity
- AA 320-429
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9
- Brand
- PicoKine™
- Analytical Method
- Quantitative
- Specificity
- Expression system for standard: CHO, Immunogen sequence: S320-R429
- Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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- Target See all GDF2 ELISA Kits
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Alternative Name
- GDF2 (GDF2 Products)
- Synonyms
- bmp9 ELISA Kit, BMP-9 ELISA Kit, BMP9 ELISA Kit, Bmp9 ELISA Kit, DSL1 ELISA Kit, growth differentiation factor 2 ELISA Kit, gdf2 ELISA Kit, GDF2 ELISA Kit, Gdf2 ELISA Kit
- Background
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Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.
Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,
Full Gene Name: growth differentiation factor 2
Cellular Localisation: Secreted - UniProt
- Q9UK05
- Pathways
- Transition Metal Ion Homeostasis
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