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GDF2 ELISA Kit

GDF2 Reactivity: Human AA 320-429 Colorimetric Sandwich ELISA
Catalog No. ABIN5510718
  • Target See all GDF2 ELISA Kits
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Binding Specificity
    AA 320-429
    Reactivity
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: CHO, Immunogen sequence: S320-R429
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all GDF2 ELISA Kits
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Alternative Name
    GDF2 (GDF2 Products)
    Synonyms
    bmp9 ELISA Kit, BMP-9 ELISA Kit, BMP9 ELISA Kit, Bmp9 ELISA Kit, DSL1 ELISA Kit, growth differentiation factor 2 ELISA Kit, gdf2 ELISA Kit, GDF2 ELISA Kit, Gdf2 ELISA Kit
    Background

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted
    UniProt
    Q9UK05
    Pathways
    Transition Metal Ion Homeostasis
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