APCS ELISA Kit

Catalog No. ABIN5510715

Product Details APCS ELISA Kit

Target: APCS (Amyloid P Component, Serum (APCS))

Binding Specificity: AA 20-223

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human SAP/PTX2

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: E.coli
Immunogen sequence: H20-V223

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Found in serum and urine. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Alternative Name: APCS (APCS Products)

Synonyms: PTX2 ELISA Kit, SAP ELISA Kit, Sap ELISA Kit, APCS ELISA Kit, FP ELISA Kit, SAP(FP) ELISA Kit, apcs ELISA Kit, ptx2 ELISA Kit, sap ELISA Kit, amyloid P component, serum ELISA Kit, serum amyloid P-component ELISA Kit, amyloid P component, serum protein L homeolog ELISA Kit, APCS ELISA Kit, Apcs ELISA Kit, apcs.L ELISA Kit

Background:

Protein Function: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened i²-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Synonyms: Serum amyloid P-component,SAP,9.5S alpha-1-glycoprotein,Serum amyloid P-component(1-203),APCS,PTX2,

Full Gene Name: Serum amyloid P-component

Cellular Localisation: Secreted.

UniProt: P02743