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GREM2 ELISA Kit

GREM2 Reactivity: Rabbit AA 22-168 Colorimetric Sandwich ELISA
Catalog No. ABIN5510700
  • Target See all GREM2 ELISA Kits
    GREM2 (Gremlin 2 (GREM2))
    Binding Specificity
    AA 22-168
    Reactivity
    • 3
    • 3
    • 1
    Rabbit
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit GREM2
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: E.coli
    Immunogen sequence: R22-Q168
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Top Product
    Discover our top product GREM2 ELISA Kit
  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all GREM2 ELISA Kits
    GREM2 (Gremlin 2 (GREM2))
    Alternative Name
    GREM2 (GREM2 Products)
    Synonyms
    prdc ELISA Kit, zgc:112207 ELISA Kit, RGD1560008 ELISA Kit, Gremlin2 ELISA Kit, Prdc ELISA Kit, CKTSF1B2 ELISA Kit, DAND3 ELISA Kit, PRDC ELISA Kit, gremlin 2, DAN family BMP antagonist ELISA Kit, gremlin 2, DAN family BMP antagonist b ELISA Kit, gremlin 2, cysteine knot superfamily ELISA Kit, GREM2 ELISA Kit, grem2b ELISA Kit, grem2 ELISA Kit, Grem2 ELISA Kit
    Background

    Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). .

    Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.

    Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,DAN domain family member 3,Protein related to DAN and cerberus,GREM2,CKTSF1B2, DAND3, PRDC,

    Full Gene Name: Gremlin-2

    Cellular Localisation: Secreted.
    UniProt
    Q9H772
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