MUC16 ELISA Kit
(1 reference)-
- Target See all MUC16 (CA125) ELISA Kits
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- Binding Specificity
- AA 21005-21992
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human CA125/MUC16
- Brand
- PicoKine™
- Analytical Method
- Quantitative
- Specificity
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Expression system for standard: CHO
Immunogen sequence: M21005-Q21992 - Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Characteristics
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Tissue Specificity: Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. .
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Mucin 16, Cell Surface Associated (CA125) ELISA Kit
CA125 Reactivity: Human Colorimetric Sandwich ELISA 1.56 U/mL - 100 U/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Mucin 16, Cell Surface Associated (CA125) ELISA KitCA125 Reactivity: Mouse Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Mucin 16, Cell Surface Associated (CA125) ELISA KitCA125 Reactivity: Rat Colorimetric Sandwich ELISA 7.813 IU/mL - 500 IU/mL Plasma, Serum, Tissue Homogenate
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- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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: "TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 96035-96047, (2017) (PubMed).
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: "TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 96035-96047, (2017) (PubMed).
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- Target See all MUC16 (CA125) ELISA Kits
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- Alternative Name
- MUC16 (CA125 Products)
- Background
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Protein Function: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. .
Background: CA-125, also known as mucin 16 or MUC16, is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. It is a component of the ocular surface, the respiratory tract and the female reproductive tract epithelia. Since MUC16 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. Also, the cytoplasmic tail of MUC16 has been shown to interact with cytoskeleton by binding members of the ERM protein family. The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers.
Synonyms: Mucin-16 ,MUC-16,Ovarian cancer-related tumor marker CA125 ,CA-125 ,Ovarian carcinoma antigen CA125 ,MUC16 ,CA125 ,
Full Gene Name: Mucin-16
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain. - UniProt
- Q8WXI7
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