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Hemopexin ELISA Kit

HPX Reactivity: Human AA 24-462 Colorimetric Sandwich ELISA
Catalog No. ABIN5510645
  • Target See all Hemopexin (HPX) ELISA Kits
    Hemopexin (HPX)
    Binding Specificity
    AA 24-462
    Reactivity
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Hemopexin
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: NSO
    Immunogen sequence: T24-H462
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Characteristics

    Tissue Specificity: Expressed by the liver and secreted in plasma.

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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all Hemopexin (HPX) ELISA Kits
    Hemopexin (HPX)
    Alternative Name
    HPX (HPX Products)
    Synonyms
    HPX ELISA Kit, HX ELISA Kit, Hpxn ELISA Kit, hx ELISA Kit, wu:fi17f11 ELISA Kit, wu:fi19a10 ELISA Kit, hemopexin ELISA Kit, HPX ELISA Kit, Mmar10_1124 ELISA Kit, Hpx ELISA Kit, hpx ELISA Kit
    Background

    Protein Function: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

    Background: Hemopexin (or haemopexin, HPX), also known as beta-1B-glycoprotein, is a protein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins. Hemopexin binds heme with the highest affinity of any known protein. Its function is scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin and thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells. This function of hemopexin is to preserve the body's iron.

    Synonyms: Hemopexin,Beta-1B-glycoprotein,HPX,

    Full Gene Name: Hemopexin

    Cellular Localisation: Secreted.
    UniProt
    P02790
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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