FABP2 ELISA Kit

Catalog No. ABIN5510632

Product Details FABP2 ELISA Kit

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Binding Specificity: AA 2-132

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human FABP2/I-FABP

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: E.coli
Immunogen sequence: A2-D132

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Alternative Name: FABP2 (FABP2 Products)

Background:

Protein Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Background: Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP) is a protein that in humans is encoded by the FABP2 gene. The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. Using a human cDNA probe for in situ hybridization studies, they regionalized the assignment to 4q28-q31. The intestinal form of FABP was mapped to mouse chromosome 3 between the amylase and alcohol dehydrogenase-3 loci. Also, they may be responsible in the modulation of cell growth and proliferation.

Synonyms: Fatty acid-binding protein, intestinal,Fatty acid-binding protein 2,Intestinal-type fatty acid-binding protein,I-FABP,FABP2,FABPI,

Full Gene Name: Fatty acid-binding protein, intestinal

Cellular Localisation: Cytoplasm.

UniProt: P12104