Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Epiregulin ELISA Kit

EREG Reactivity: Pig AA 60-108 Colorimetric Sandwich ELISA
Catalog No. ABIN5510630
  • Target See all Epiregulin (EREG) ELISA Kits
    Epiregulin (EREG)
    Binding Specificity
    AA 60-108
    Reactivity
    • 9
    • 8
    • 4
    • 1
    Pig
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine Epiregulin
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    E.coli, V60-L108
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Characteristics

    Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .

    Featured
    Discover our best selling EREG ELISA Kit
    Top Product
    Discover our top product EREG ELISA Kit
  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all Epiregulin (EREG) ELISA Kits
    Epiregulin (EREG)
    Alternative Name
    EREG (EREG Products)
    Background

    Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .

    Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.

    Synonyms: Proepiregulin,Epiregulin,EPR,EREG,

    Full Gene Name: Proepiregulin

    Cellular Localisation: Epiregulin: Secreted, extracellular space.
    UniProt
    O14944
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
You are here:
Support