Epiregulin ELISA Kit
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- Target See all Epiregulin (EREG) ELISA Kits
- Epiregulin (EREG)
- Binding Specificity
- AA 60-108
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Reactivity
- Pig
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine Epiregulin
- Brand
- PicoKine™
- Analytical Method
- Quantitative
- Specificity
- E.coli, V60-L108
- Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Characteristics
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Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .
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- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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- Target See all Epiregulin (EREG) ELISA Kits
- Epiregulin (EREG)
- Alternative Name
- EREG (EREG Products)
- Synonyms
- EREG ELISA Kit, ER ELISA Kit, EPR ELISA Kit, proepiregulin ELISA Kit, epiregulin ELISA Kit, EREG ELISA Kit, ereg ELISA Kit, Ereg ELISA Kit
- Background
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Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .
Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.
Synonyms: Proepiregulin,Epiregulin,EPR,EREG,
Full Gene Name: Proepiregulin
Cellular Localisation: Epiregulin: Secreted, extracellular space. - UniProt
- O14944
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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