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TIMP3 ELISA Kit

TIMP3 Reactivity: Horse AA 24-211 Colorimetric Sandwich ELISA
Catalog No. ABIN5510570
  • Target See all TIMP3 ELISA Kits
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Binding Specificity
    AA 24-211
    Reactivity
    • 11
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Horse
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine TIMP-3
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: NSO
    Immunogen sequence: C24-P211
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Characteristics

    Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family.

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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all TIMP3 ELISA Kits
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Alternative Name
    TIMP3 (TIMP3 Products)
    Synonyms
    TIMP-3 ELISA Kit, TIMP3 ELISA Kit, timp3 ELISA Kit, HSMRK222 ELISA Kit, K222 ELISA Kit, K222TA2 ELISA Kit, SFD ELISA Kit, IMP-3 ELISA Kit, timp3-A ELISA Kit, Timp-3 ELISA Kit, metalloproteinase inhibitor 3 ELISA Kit, TIMP metallopeptidase inhibitor 3 ELISA Kit, Metalloproteinase inhibitor 3 ELISA Kit, TIMP metallopeptidase inhibitor 3 L homeolog ELISA Kit, tissue inhibitor of metalloproteinase 3 ELISA Kit, CpipJ_CPIJ003282 ELISA Kit, TIMP3 ELISA Kit, timp3 ELISA Kit, Timp3 ELISA Kit, timp3.L ELISA Kit
    Background

    Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

    Background: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).

    Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,

    Full Gene Name: Metalloproteinase inhibitor 3

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    P35625
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