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Rheumatoid Factor ELISA Kit

RF Reactivity: Mouse Colorimetric Sandwich ELISA Serum
Catalog No. ABIN5068389
  • Target See all Rheumatoid Factor (RF) products
    Rheumatoid Factor (RF)
    Reactivity
    • 2
    • 1
    • 1
    Mouse
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Sample Type
    Serum
    Characteristics
    Rheumatoid Factor (RF), Mouse, ELISA Kit
    Components
    • Microwell Strips, 1x96 wells
    • Negative Control, 1x1ml
    • Positive Control, 1x1ml
    • Sample Diluent, 10X, 1x10ml
    • IgG (HRP), 100X GtxMo, 1x200ul
    • Wash Buffer, 100X, 1x10ml
    • TMB Substrate, 1x12ml
    • Stop Solution. 1x12ml
    Featured
    Discover our best selling RF ELISA Kit
  • Restrictions
    For Research Use only
  • Storage
    4 °C
    Storage Comment
    4°C
  • Target See all Rheumatoid Factor (RF) products
    Rheumatoid Factor (RF)
    Abstract
    RF Products
    Background
    Rheumatoid Factors (RFs) were described as Immunoglobulins (IgGs) in rheumatoid arthritis as detected by agglutination of rabbit IgG coated erythrocytes. It was later demonstrated that RFs were IgM molecules reactive with the Fc-portion of the IgG from various species. In addition to the IgM RF, subsequent studies have identified RFs of other IgG subtypes (IgG, IgA, and IgE) in sera of patients with rheumatoid arthritis, and certain other chronic diseases. Most commercial assays measure predominantly IgM RFs. It has been observed that measurement of IgG RF may be a better indicator of rheumatoid arthritis than IgM RF. IgA RF and IgE RF have been implicated in articular disease process in rheumatoid arthritis and rheumatoid vasculitis, respectively. RFs, produced by cells within the joint space, are found in joint fluids as well. RF titer, particularly IgG RF correlate with the intensity of synovitis.
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