Thymic Stromal Lymphopoietin ELISA Kit
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- Target See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits
- Thymic Stromal Lymphopoietin (TSLP)
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Reactivity
- Mouse
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 0.02-1.0 ng/mL
- Minimum Detection Limit
- 0.02 ng/mL
- Application
- ELISA
- Sample Type
- Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
- Analytical Method
- Quantitative
- Specificity
- Natural and recombinant Mouse TSLP Ligand
- Sensitivity
- 7 pg/mL
- Material not included
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
- Top Product
- Discover our top product TSLP ELISA Kit
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Thymic Stromal Lymphopoietin (TSLP) ELISA Kit
TSLP Reactivity: Human Colorimetric Sandwich ELISA 62.5 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitHigh Sensitivity TSLP Reactivity: Human Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Human Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma, Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Monkey Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Mouse Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Rat Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Mouse AA 20-140 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Human AA 29-159 Colorimetric Sandwich ELISA 31.2-2000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Human Colorimetric Sandwich ELISA 3.9-250 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP Reactivity: Human Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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- Application Notes
- Detection Wavelength: 450 nm
- Sample Volume
- 20 μL
- Assay Time
- 3 h
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C
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- Target See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits
- Thymic Stromal Lymphopoietin (TSLP)
- Alternative Name
- TSLP (TSLP Products)
- Background
- Thymic Stromal Lymphopoietin (TSLP) is a member of the B cell-stimulating factor family. Originally identified from the conditioned medium of a mouse thymic stromal cell line that promoted B-cell development, TSLP is expressed in thymus, spleen, kidney, lung, and bone marrow. Mouse TSLP cDNA encodes a 140 amino acid (aa) residue precursor protein with a 19 aa signal sequence. TSLP activity overlaps with that of IL-7, playing a key role in the development of B cells, as well as stimulating the growth of thymocytes and T cells. TSLP stimulates monocytes to produce T cell-attracting chemokines such as TARC (CCL17) and MDC (CCL22). TSLP also activates dendritic cell-primed CD4 T cells to produce Th2 cytokines, including IL-4, IL-5, IL-13, and TNFα. This hematopoietic cytokine binds to a heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rα) and the TSLP-specific chain (TSLPR). Binding induces activation of STAT3 and STAT5 via phosphorylation. Mouse TSLP shares approximately 43 % amino acid sequence identity with human TSLP.
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